British Journal of Clinical Pharmacology, EarlyView.Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta +5 more
wiley +1 more source
A new era for ICU-acquired weakness research-from mechanisms to meaningful recovery. [PDF]
Intensive Care MedPiva S, Langouche L, Mohammed A.
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić +7 more
wiley +1 more source
Effects of personalized strength training on isokinetic muscle strength and balance ability among fencers with chronic ankle instability. [PDF]
Sci RepLiao L, He L, Zhao W, Liu M, Xu J.
europepmc +1 more source
Learner emotions and performance in hypercasual VR games with adaptive AI difficulty
British Educational Research Journal, EarlyView.Abstract Hypercasual virtual reality games (HVRGs) are widely regarded as cost‐effective tools for rapid skill acquisition, yet the mechanisms that optimise their effectiveness and user acceptance remain insufficiently explored. This mixed‐methods empirical study investigates how playful emotions, characterised by engagement, enjoyment and anxiety ...
Zeeshan Ahmed, Faizan Ahmad, Chen Hui
wiley +1 more source
Comparative efficacy of different digital health intervention modalities versus traditional pulmonary rehabilitation on daily step counts and exercise capacity in patients with COPD: a systematic review and network meta-analysis. [PDF]
Front Public HealthXu Y, Liao M, Bai J.
europepmc +1 more source
Rehabilitation for visual impaired persons
Annals of Physical and Rehabilitation Medicine, 2014 openaire +1 more source
British Educational Research Journal, EarlyView.Abstract Wellbeing in higher education (HE) in the United Kingdom has been increasingly prioritised for many institutions, with a growing demand for student support requests. There are various determinants in life that can influence mental health. As such, protected characteristics, including race, can indicate that students who are Black or Asian ...
Amy Bywater, Helen Keane
wiley +1 more source
Magnetic resonance imaging tissue bridges: An emerging biomarker for prognostication in traumatic spinal cord injury. [PDF]
World J OrthopPeng Y, Luo NN, Gan L, Zhang JQ.
europepmc +1 more source
Young people's occupational aspirations beyond the aspiration discourse: A sociocultural perspective
British Educational Research Journal, EarlyView.Abstract Young people's aspirations have been the focus of many educational, sociological and psychological studies. This paper argues, firstly, that the concept of aspirations holds greater generative potential than suggested by the policy‐oriented ‘aspiration discourse’.
Jelena Popov
wiley +1 more source