Results 171 to 180 of about 2,782,172 (355)

Empathy mapping and hybrid persona creation: Understanding older adults' needs in technology design for ageing in place. [PDF]

Comput Struct Biotechnol J
Kastl A.
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Expansion of Personas to Guide Professional Development in Implementing Evidence-Based Practices in Diverse Institutions. [PDF]

CBE Life Sci Educ
Dunbar-Wallis AK, Zagallo P, Meeder A, Schwartz Z, Groenevelt E, Bilinski T, Jaeger D, Corwin L.   +7 more
europepmc   +1 more source

EDUCACIÓN ARTÍSTICA EN PERSONAS CON DEMENCIA TEMPRANA

, 2016
Lorena López Méndez
openalex   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

[Factors associated with cardiometabolic disease screening in older adults in the Peruvian AmazonFatores associados ao rastreamento de doenças cardiometabólicas em pessoas idosas da Amazônia peruana]. [PDF]

Rev Panam Salud Publica
Ñaña-Cordova AM, Macavilca-Toribio MA, Reyna-Ruiz VL, Oria-Morales M, Gonzales-Espinoza AJ, Parodi JF, Camacho-Caballero K, Runzer-Colmenares FM.   +7 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

[Current Challenges in HIV Healthcare: Moving Towards the Eradication of Stigma]. [PDF]

Aten Primaria
Koerting A, Mascort J, Del Amo J.
europepmc   +1 more source

Personas que conectan con personas :

En Publicidad y Relaciones Públicas, no basta con saber comunicar; hay que conectar. La Inteligencia Emocional es una competencia clave en este ámbito, pero su enseñanza sigue siendo una asignatura pendiente en la universidad. Para abordar esta carencia, se diseña un manual educativo que integra la Inteligencia Emocional como una competencia esencial ...
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source