The Patient Persona of the Self-Management Experience of Home-Based Rehabilitation for Spinal Cord Injury Patients: A Qualitative Study [Letter]. [PDF]
Patient Prefer AdherenceLiu X, Ning L.
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Amplifying missing voices in healthcare research: an AI framework for co-production of PPIE. [PDF]
Front Digit HealthSteele A +3 more
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Confusion and information triggered by photos in persona profiles [PDF]
, 2019 An, Jisun +5 more
core +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
[Critical analysis of the conceptualization of work among older adults in the contemporary era]. [PDF]
Cad Saude PublicaGonzález-Ulloa JR +4 more
europepmc +1 more source
Personas adultas mayores como dinamizadoras sociales. Un proyecto de intervención sociodeducativa desde la universidad [PDF]
, 2017 Cárdenas Rodríguez, Rocío +1 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Tailored personas for self-management in home-based rehabilitation for participants with lower limb lymphedema: A qualitative study. [PDF]
Int J Nurs Stud AdvYin Y +5 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source