Results 261 to 270 of about 2,666,075 (354)
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
[Digitalization and access as a means of responding to health care practices: from Adolescence to Old Age] [PDF]
Gutierrez Quiceno B +2 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cardia-AI: Passive Cardiac Event Monitoring Using Smartwatch Sensors and Predictive Analysis via Large Language Models. [PDF]
Momin EA, Mansoor H.
europepmc +1 more source
Percepción de riesgo de desarrollar diabetes mellitus en personas no diabéticas
Belkis Vicente Sánchez +4 more
openalex +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Pain in Long COVID: A scoping review of clinical characteristics and patterns of manifestation. [PDF]
La Scaléa ACR, Uehara SCDSA.
europepmc +1 more source

