Results 261 to 270 of about 2,419,473 (338)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Gepants: Key Features of A Potent Therapeutic Option and Considerations in The Latin American Context. [PDF]
Rev NeurolPatiño DR, Zapata JC, Aguirre ALV.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Vacunación contra el VPH en varones: una estrategia incompleta en la lucha por la salud pública. [PDF]
Rev Panam Salud PublicaVilchez ND.
europepmc +1 more source
Las ganancias de capital en el Impuesto sobre la Renta de las Personas Físicas
, 1996 Eduardo Sanz Gadea
openalex +2 more sources