Results 41 to 50 of about 2,666,075 (354)
Si la fidelidad es solo una virtud o algo más según Leonardo Polo
En este trabajo se defiende, según la filosofía de L. Polo, que, aunque la fidelidad se suele referir al trato con cosas, propiamente se refiere a las personas, y en especial a Dios.
Juan Fernando Sellés Dauder +1 more
doaj +1 more source
El presente artículo es producto de una revisión bibliográfica, cuyo objetivo consistió en analizar los conceptos de persona y personas jurídicas. Se aplicó el método de análisis, con un enfoque cualitativo, diseño no experimental, bajo un nivel documental-bibliográfico transversal.
openaire +2 more sources
A hermeneutic inquiry into user-created personas in different Namibian locales [PDF]
Persona is a tool broadly used in technology design to support communicational interactions between designers and users. Different Persona types and methods have evolved mostly in the Global North, and been partially deployed in the Global South every so
Bidwell N. J. +7 more
core +2 more sources
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Una escuela de todas (las personas) para todas (las personas) [PDF]
Escuela 2 representa una particular manera de entender la educación. Un proyecto educativo nacido de la cooperación entre las personas, concebido para albergar todo un universo de realidades y gestionado de manera colaborativa bajo los principios de la ...
Cervellera Martínez, Luiso +1 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source

