Results 51 to 60 of about 2,557,779 (357)

Positive Personas: Integrating Well-being Determinants into Personas [PDF]

open access: yesarXiv: Human-Computer Interaction, 2017
System design for well-being needs an appropriate tool to help designers to determine relevant requirements that can help human well-being to flourish. Personas come as a simple yet powerful tool in the early development stage of the user interface design.
Jan M. Pawlowski   +2 more
openaire   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Persona y Persona Jurídica

open access: yesRevista Ciencia Jurídica y Política, 2018
El presente artículo es producto de una revisión bibliográfica, cuyo objetivo consistió en analizar los conceptos de persona y personas jurídicas. Se aplicó el método de análisis, con un enfoque cualitativo, diseño no experimental, bajo un nivel documental-bibliográfico transversal.
openaire   +2 more sources

Personas con disminución [PDF]

open access: yes, 1999
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Planella i Carm, Jordi
core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Los minerales son inocentes; las personas, no (minerales y personas) [PDF]

open access: yes, 2008
Se proponen una serie de temas para hacer pequeños trabajos de aula o de investigación complementarios a la materia Biología y Geología. Son temas que relacionan, por una parte, el uso de los minerales en la vida diaria y, por otra, la extracción de los ...
Consorci del Museu de Ciències Naturals de Barcelona   +2 more
core  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Una escuela de todas (las personas) para todas (las personas) [PDF]

open access: yes, 2008
Escuela 2 representa una particular manera de entender la educación. Un proyecto educativo nacido de la cooperación entre las personas, concebido para albergar todo un universo de realidades y gestionado de manera colaborativa bajo los principios de la ...
Cervellera Martínez, Luiso   +1 more
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

From Persona to Techsona [PDF]

open access: yes, 2013
In this paper we introduce the notion of techsona, as a possible counterpart design instrument to personas. We use a case study to illustrate a design process where techsonas help pinpoint technological ideas and alternatives and analyze these systematically.
Bødker, Susanne   +1 more
openaire   +3 more sources

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