Results 81 to 90 of about 2,419,473 (338)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Revista Projetar, 2019 Reflecciones sobre el concepto de Lugar y su influencia en el proceso proyectual arquitectónico, se hace un barrido amplio sobre sus características más influyentes en un proyecto que se incerte en un lugar.
Carlos Martín Pagano Conesa +2 more
doaj
Los minerales son inocentes; las personas, no (minerales y personas) [PDF]
, 2008 Se proponen una serie de temas para hacer pequeños trabajos de aula o de investigación complementarios a la materia Biología y Geología. Son temas que relacionan, por una parte, el uso de los minerales en la vida diaria y, por otra, la extracción de los ...
Consorci del Museu de Ciències Naturals de Barcelona +2 more
core
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Una escuela de todas (las personas) para todas (las personas) [PDF]
, 2008 Escuela 2 representa una particular manera de entender la educación. Un proyecto educativo nacido de la cooperación entre las personas, concebido para albergar todo un universo de realidades y gestionado de manera colaborativa bajo los principios de la ...
Cervellera Martínez, Luiso +1 more
core +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Cracking the AIEd code: Dialogic-relational academic advising
Ubiquity ProceedingsTo contribute to cracking the theoretical AI in education code, interviews with academic advisors at a European university were analysed using a dialogic-relational translation device to develop a sociomaterial framework for building EdTech and AIEd ...
Jan Petrus Bosman +3 more
doaj +1 more source
ARS Medica, 2008 Se aborda el tema desde la perspectiva del Derecho Constitucional, refiriéndose, por una parte, al carácter de personas que nuestra Carta Fundamental reconoce a los niños y adolescentes; sobre la base de la dignidad humana, los niños son personas ...
Miguel Ángel Fernández González
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source