Results 81 to 90 of about 2,796,276 (306)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Los minerales son inocentes; las personas, no (minerales y personas) [PDF]

, 2008
Se proponen una serie de temas para hacer pequeños trabajos de aula o de investigación complementarios a la materia Biología y Geología. Son temas que relacionan, por una parte, el uso de los minerales en la vida diaria y, por otra, la extracción de los ...
Consorci del Museu de Ciències Naturals de Barcelona, Curto, Carles, Santó, Rosa   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The power of personas: Exploring an innovative model for understanding stakeholder perspectives in an oncology learning health network

Learning Health Systems
Introduction Learning health networks (LHNs) improve clinical outcomes by applying core tenets of continuous quality improvements (QI) to reach community‐defined outcomes, data‐sharing, and empowered interdisciplinary teams including patients and ...
Dylan J. Cooper, Jessie Karten, Sarah E. Hoffe, Daniel A. King, Matthew Weiss, Danielle K. DePeralta, Andrew L. Coveler, Sunil R. Hingorani, Tracey Shefter, Cheryl Meguid, Hannah Roberts, Theodore S. Hong, Amol Narang, Amy Hacker‐Prietz, George A. Fisher, Jay Sandler, Laurie Singer, Bobby Korah, William Hoos, Carrie T. Stricker, Joseph M. Herman   +20 more
doaj   +1 more source

Cracking the AIEd code: Dialogic-relational academic advising

Ubiquity Proceedings
To contribute to cracking the theoretical AI in education code, interviews with academic advisors at a European university were analysed using a dialogic-relational translation device to develop a sociomaterial framework for building EdTech and AIEd ...
Jan Petrus Bosman, Wim van Petegem, Tinne de Laet, Nompilo Tshuma   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Detrás de la economía hay personas

Ensayos Pedagógicos, 2003
En todas las sociedades y en todas las unidades familiares, las personas deben enfrentarse diariamente a la toma de decisiones sobre cómo obtener óptimo a partir de cada una de sus acciones.
Laura Arias Pacheco
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

El concepto de formación en el movimiento de vida independiente.

Revista Kavilando, 2014
El Movimiento de Vida Independiente es un movimiento pensado y ejecutado por personas con discapacidad de diferentes lugares, con el objetivo de reivindicar la concepción de dichas personas, logrando y exigiendo una verdadera inclusión social como ...
Sandra Milena Bedoya, Nathalie Taborda, Carlos Alberto Hincapié Ospina   +2 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source