Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres +8 more
wiley +1 more source
Knowledge, attitude, and self-care practice regarding glaucoma among hospital workers at a tertiary center in South-South Nigeria. [PDF]
Ndife TI.
europepmc +1 more source
Global Trends and Advances in Traumatic Brain Injury
ABSTRACT Traumatic brain injury (TBI) remains a major global public health challenge, contributing substantially to morbidity and mortality while imposing a significant socioeconomic burden. In recent years, notable progress has been made in understanding TBI pathophysiology, classification, monitoring, and treatment.
Yuan Zhuang +3 more
wiley +1 more source
Analysis of DRG remuneration of acute fracture procedures versus elective total arthroplasty for the German health care system - Is elective total arthroplasty really more cost-effective? [PDF]
Hierl K, Kerschbaum M, Baumann F, Alt V.
europepmc +1 more source
ABSTRACT In response to growing global challenges, this study explores how social entrepreneurship within the Edible City movement contributes to building resilient, sustainable, and equitable urban food systems. Drawing on semistructured interviews with over 70 stakeholders across five cities—Berlin, Andernach, Oslo, Rotterdam, and Havana—we ...
Ina Säumel +6 more
wiley +1 more source
A Time-Driven Activity-Based Costing Analysis of Minor Hand Procedure Room Utilization at a Single Military Institution. [PDF]
Serhan KA +3 more
europepmc +1 more source
ABSTRACT This study examines the impact of self‐checkout technology implementation on B2B customer shopping behavior using a novel methodological approach that combines propensity score matching with difference‐in‐differences analysis on actual point‐of‐sale transaction data.
Jindřich Špička +1 more
wiley +1 more source
Evaluating the effectiveness of the SHEL model in reducing occupational exposure risks among pre-hospital emergency personnel: a retrospective cohort study (2018-2024). [PDF]
Li Y, Hou X, Qin M.
europepmc +1 more source

