Results 121 to 130 of about 225,477 (288)
Advanced Science, EarlyView.Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu +11 more
wiley +1 more source
An AHP-based Decision Support System for Personnel Selection for Manager Position in Businesses [PDF]
Annals of Computer Science and Information Systems, 2022 Muhammed Hanefi Calp, Shivani Agarwal
openaire +2 more sources
ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
Advanced Science, EarlyView.This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Meikuang AnquanPersonnel trajectory playback is an important function of the precise positioning system for underground personnel in coal mines. Aiming at the huge amount of data in the precise positioning system of coal mines, which leads to problems such as long ...
Chenwu ZHU
doaj +1 more source
Speech Recognition Technology: Improving Speed and Accuracy of Emergency Medical Services Documentation to Protect Patients [PDF]
, 2018 Because hospital errors, such as mistakes in documentation, cause one in six deaths each year in the United States, the accuracy of health records in the emergency medical services (EMS) must be improved.
Tran, Tan
core +2 more sources
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Advanced Science, EarlyView.Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
Helicopter anti-torque system using fuselage strakes [PDF]
, 1987 The improvement of the helicopter torque control system is discussed. At low to medium forward speeds helicopter performance is limited by the effectiveness of the means for counteracting main rotor torque and controlling sideslip airloads.
Kelley, Henry L., Wilson, John C.
core +1 more source
Advanced Science, EarlyView.A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen +12 more
wiley +1 more source
Surveyor mission operations system. Space flight operations memorandum Surveyor 7 [PDF]
Surveyor Mission G flight operations from transit phase to second lunar ...
Callan, R.
core +1 more source