Results 31 to 40 of about 28,359 (215)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Application of Kalman filter in underground personnel tracking and positioning

open access: yesGong-kuang zidonghua, 2013
In view of problem that RSSI location algorithm does not have continuity in positioning process, the paper proposed an underground personnel positioning method with continuity based on Kalman filter.
LUO Yu-feng, LIU Yong, LI Fang
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Design of factory personnel safety and protection location system based on TDOA technology

open access: yesDianzi Jishu Yingyong, 2018
Aiming at the problems such as a great amount of personnel in large modern factory, complicated management of complex company types and frequent accidents, a design scheme of factory security and protection positioning system which can accurately locate ...
Hu Zifei   +3 more
doaj   +1 more source

A Visible Light 3D Positioning System for Underground Mines Based on Convolutional Neural Network Combining Inception Module and Attention Mechanism

open access: yesPhotonics, 2023
To improve the accuracy of personnel positioning in underground coal mines, in this paper, we propose a convolutional neural network (CNN) three-dimensional (3D) visible light positioning (VLP) system based on the Inception-v2 module and efficient ...
Bo Deng   +3 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Application of improved analytic hierarchy process in the emergency treatment mechanism of precise personnel positioning system

open access: yesGong-kuang zidonghua, 2021
In order to solve the problem of misjudgment of underground personnel in distress in the intelligent mining precise personnel positioning system, resulting in a waste of rescue resources, this paper proposes to apply the analytic hierarchy process to the
TANG Lijun1, WU Wei2, LIU Shisen3
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

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