Results 131 to 140 of about 4,434,775 (339)

Living in a “Parallel World”: Disability in Post-Soviet Ukraine [PDF]

open access: yes, 2002
[Excerpt] These are challenges that are familiar to disabled people all over the world. Challenges such as these make many persons with disabilities in Ukraine feel as if they live in a “parallel world,” one separate from that enjoyed by “able-bodied ...
Phillips, Sarah D
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Human Persons as Social Entities

open access: yesJournal of Social Ontology, 2014
The aim of this article is to show that human persons belong, ontologically, in social ontology. After setting out my views on ontology, I turn to persons and argue that they have first-person perspectives in two stages (rudimentary and robust ...
Lynne Rudder Baker
doaj  

A preliminary report on the Rural Neighbourhood Development Project in Tuen Mun and Yuen Long : implementation and achievement

open access: yes, 2019
With funding support from the Hong Kong Jockey Club Charities Trust, the Asia-Pacific Institute of Ageing Studies (APIAS) of Lingnan University collaborated with Tuen Tsz Wai San Hing Tsuen Tsing Chuen Wai Rural Community Service Centre of Yan Oi Tong ...
Asia Pacific Institute of Ageing Studies
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Assessment of the Effectiveness and Safety of Wheelchair Use Training for Patients with Hemiparesis

open access: yesВестник восстановительной медицины
INTRODUCTION. The rationale of the research is defined by the large number of patients with hemiparesis, unable to restore an upright posture and in need of training to use a wheelchair. AIM.
Nina G. Konovalova   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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