Results 171 to 180 of about 845,733 (267)

Health-Related Quality of Life Changes in Patients with Digestive Cancers and Chronic Digestive Diseases: A Prospective, Multicenter Study. [PDF]

J Clin Med
Martín J, Larrea N, García Y, Bolinaga I, Perales A, Sarasqueta C, González-Pinto A, Quintana JM.   +7 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Serologic Evidence of Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Veterinary Professional Exposed to an Infected Domestic Cat - Los Angeles County, California, December 2024-January 2025. [PDF]

MMWR Morb Mortal Wkly Rep
Vaughan A, Joyce A, Traub E, Jae M, Beeler E, Paiva E, Ananian K, Holiday C, Jefferson S, Richardson J, Munna C, Chan C, Scott T, Kojima N, Seneviratne T, Mellis A, Olsen SJ, Green N, Feaster M, Terashita D, Balter S, Levine MZ, Middleton J, de St Maurice A.   +23 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Public policies for the promotion of paralympic sport in Latin America: a comparative analysis of 10 countries. [PDF]

Front Sports Act Living
Revuelta B, Hernández R.
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Projected Outcomes of Reducing Federal Funding for Syringe Service Programs via Executive Order.

JAMA Netw Open
Fetters KB, Padmanabhan P, Yamkovoy K, Guan X, Scott SE, Kerr L, Joseph K, Day GL, Plesons M, Bartholomew TS, Tookes HE, Al-Tayyib A, Barocas JA.   +12 more
europepmc   +1 more source

Emergency Department Visits for Suspected Suicide Attempts - United States, 2021-2025. [PDF]

MMWR Morb Mortal Wkly Rep
Singichetti B, Cammack AL, Rekieta P, Schumacher A, van Santen KL, Kaczkowski W, Radhakrishnan L, Anderson KN, Ballesteros MF, Lee R.   +9 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Participatory priority setting of research questions for improving hospital care of adults with childhood-onset intellectual disabilities (PRISMA): a study protocol for a mixed-methods study. [PDF]

BMJ Open
Scheffel A, Fritsch T, Arnold S, Asam T, Bettenhausen B, Dengler B, Einsmehr V, Spielmann J, Weidmann A, Winterholler M, Prodinger B.   +10 more
europepmc   +1 more source