Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Both symbolic and embodied representations contribute to spatial language processing: Evidence from younger and older adults [PDF]
, 2015 Building on earlier neuropsychological work, we adopted a novel individual differences approach to examine the relationship between spatial language and a wide range of both verbal and nonverbal abilities.
Coventry, Kenny +3 more
core
Creating a Culture of Thinking that Cultivates the Perspective-Taking Disposition [PDF]
, 2013 Through action research, the researchers engaged a group of third grade children in a project that offered a variety of learning activities to develop the children’s perspective-taking ability. As a result the teachers found a significant increase in the
Ibañez Wolberg, Rochelle +2 more
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
The Effects of Animals on Children's Development of Perspective-Taking Abilities
, 2000 Mika Maruyama
openalex +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
TRAINING DEICTIC RELATIONS TO CHILDREN WITH DEVELOPMENTAL DELAYS THROUGH THE USE OF THE PEAK RELATIONAL TRAINING SYSTEM [PDF]
, 2015 Children with developmental delays often do not acquire perspective taking skills without training. These skills are imperative to the ability to relate to others socially and the development of appropriate social behavior.
Kime, Dena LaRae
core +1 more source
Affective perspective-taking and sympathy in young children
, 2000 Mary Driver Leinbach
openalex +2 more sources
Changing Perspectives — Changing Paradigms: Taking the "Soft Path" to Water Sustainability in the Okanagan Basin [PDF]
, 2006 Oliver M. Brandes, Lynn Kriwoken
openalex +1 more source