Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
The Ideological Turing Test: A Behavioral Measure of Open-Mindedness and Perspective-Taking. [PDF]
Brand CO, Brady D, Stafford T.
europepmc +1 more source
Modelling and Financing of Agri-environmental Measures: Assessment of Regional Preferences in Poland [PDF]
The main objective of the paper is to assess the importance of regional preferences in financing of agri-environmental measures. The analysis is based on results of a case study conducted in South-eastern Poland.
Jadwiga ZIOLKOWSKA
core
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Editorial: Virtual reality and empathy
Sofia Seinfeld +4 more
doaj +1 more source
Spatial perspective taking is impaired in spinocerebellar ataxias and Friedreich ataxia. [PDF]
Karamazovova S +9 more
europepmc +1 more source
A Dialogue between Hindu and Catholic Perspectives in Taking Care of Newborns at their End-of-Life
Giulia Adele Dinicola
openalex +2 more sources
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Spatial perspective taking and social perspective taking
openaire +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source

