NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Laplace transform-homotopy perturbation method as a powerful tool to solve nonlinear problems with boundary conditions defined on finite intervals [PDF]
This article proposes Laplace transform-homotopy perturbation method (LTHPM) to solve nonlinear differential equations with Dirichlet, mixed, and Neumann boundary conditions.
ALEJANDRO DIAZ SANCHEZ
core
Localized nodal solutions for semiclassical quasilinear Choquard equations with subcritical growth
Bo Zhang, Xiangqing Liu
doaj
Determination of the Dielectric Properties of Storage Materials for Exhaust Gas Aftertreatment Using the Microwave Cavity Perturbation Method. [PDF]
Steiner C +6 more
europepmc +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
On the Convergence of the Perturbation Method. I [PDF]
openaire +2 more sources
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Non-Hermitian Rayleigh–Schrödinger-like perturbation theory at exceptional point
We develop a Rayleigh–Schrödinger-like perturbation theory for non-Hermitian quantum systems at an exceptional point (EP) of order $N$ . Working in the Jordan basis of the unperturbed Hamiltonian and employing a Puiseux expansion of the perturbed ...
Wei-Ming Chen, Chia-Yi Ju
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source

