Results 41 to 50 of about 12,068,052 (292)

Development of a fully implicit ODE-solver for containment analysis code

open access: yesFrontiers in Energy Research
The thermal–hydraulic dynamics in containment are governed by a system of stiff ordinary differential equations (ODEs). A fully implicit discretization scheme is adopted to discretize these ODEs in order to mitigate the effects of stiffness.
Jun Huang, Jinggang Li, Yinxiang Ma
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

PERTURBATION THEORY FOR ELECTROMAGNETIC WAVE SCATTERING IN RANDOM LAYERED STRUCTURES [PDF]

open access: yes, 2010
The problem of electromagnetic wave scattering in 3-D random layered structures, is analytical treated by relying on original results of the Boundary Perturbation Theory (BPT) and Volumetric-Perturbative Reciprocal Theory (VPRT), whose structured ...
Imperatore, Pasquale
core   +1 more source

A comparison between numerical methods for solving Fuzzy fractional differential equations

open access: yesNonlinear Engineering, 2014
In this paper, numerical simulation of linear and nonlinear fuzzy initial value problems of fractional order has been done. A modificaton in the improved Euler’s method for fuzzy fractional order is proposed and utilized.
Khan Najeeb Alam   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Faster Convergent Modified Lindstedt-Poincare Solution of Nonlinear Oscillators

open access: yesUniversal Journal of Mathematics and Applications, 2020
The modified Lindstedt-Poincare method has been extended to obtain a faster convergent solution of nonlinear oscillators. First of all a classical type Lindstedt-Poincare solution has been determined and then a conversion formula has been used to find ...
Md. Nazmul Sharif   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Application of a Discontinuous Galerkin Method to Predict Airframe Noise [PDF]

open access: yes, 2009
Unstructured grids greatly ease the mesh generation process in the case of complex geometries. The Discontinuous Galerkin Method (DGM) provides a robust, high-order accurate discretization even on this type of grid.
Marcus Bauer   +5 more
core   +1 more source

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