Results 271 to 280 of about 66,753 (329)
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
Computational modeling of ATM signaling: a predictive framework for drug repurposing in ataxia-telangiectasia. [PDF]
Merulla AE +7 more
europepmc +1 more source
From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini +2 more
wiley +1 more source
Novel solitons in the (2+1)-dimensional Heisenberg spin chain via generalized conformable derivatives. [PDF]
Alam BE +2 more
europepmc +1 more source
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel +5 more
wiley +1 more source
A model to simulate human cardio-respiratory responses to airway obstruction. [PDF]
Jin X +5 more
europepmc +1 more source
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
The Wafold: Curvature-Driven Termination and Dimensional Compression in Black Holes. [PDF]
Viaña J.
europepmc +1 more source
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou +10 more
wiley +1 more source

