Results 21 to 30 of about 284,435 (176)

Treatment of deep second-degree burns on the abdomen, thighs, and genitalia: use of tilapia skin as a xenograft [PDF]

Revista Brasileira de Cirurgia Plástica, 2020
Tilapia skin has a non-infectious microbiota and a morphological structure similar to human skin. Phase II clinical studies, not yet published, have shown promising results in their use for the treatment of burns.
Edmar Maciel Lima, Manoel Odorico Moraes, Bruno Almeida Costa, Alex Marques Do Nascimento Uchôa, Camila Barroso Martins, Maria Elisabete Amaral De Moraes, Marina Becker Sales Rocha, Francisco Vagnaldo Fechine   +7 more
doaj   +1 more source

Functional Restoration of BRCA1 Nonsense Mutations by Aminoglycoside-Induced Readthrough

Frontiers in Pharmacology, 2022
BRCA1 is a major tumor suppressor that functions in the accurate repair of DNA double-strand breaks via homologous recombination (HR). Nonsense mutations in BRCA1 lead to inactive truncated protein products and are associated with high risk of breast and
Renata B. V. Abreu, Thiago T. Gomes, Thales C. Nepomuceno, Thales C. Nepomuceno, Xueli Li, Mateus Fuchshuber-Moraes, Giuliana De Gregoriis, Guilherme Suarez-Kurtz, Alvaro N. A. Monteiro, Marcelo A. Carvalho, Marcelo A. Carvalho   +10 more
doaj   +1 more source

Patterns of antenal sensilla of Panstrongylus megistus from three Brazilian states [PDF]

, 2005
The objective of the present study was to analyze and describe the phenotype of the antennal sensilla of Panstrongylus megistus, one of the epidemiologically most important species of triatomines in Brazil.
Catala, Silvia Susana, Dias, J. C. P., Juberg, J., Silva, I. G., Villela, M. M.   +4 more
core   +1 more source

Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis

Advances in Rheumatology, 2018
Objectives To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose combination of glucosamine hydrochloride and chondroitin sulfate (Cosamin DS®) in capsules
Andrea Barranjard Vannucci Lomonte, José Alexandre Mendonça, Gilberto de Castro Brandão, Marise Lazaretti Castro   +3 more
doaj   +1 more source

Quantitative G6PD Deficiency Screening in Routine Malaria Diagnostic Units in the Brazilian Amazon (SAFEPRIM): An Operational Mixed-Methods Study

Pathogens, 2022
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency testing is not routinely performed before primaquine treatment in most Plasmodium vivax endemic areas, despite the risk of primaquine-associated hemolysis.
Jose Diego Brito-Sousa, Felipe Murta, Sheila Vitor-Silva, Vanderson Sampaio, Maxwell Mendes, Brenda Souza, Talita Batista, Alicia Santos, Leonardo Marques, Laila Barbosa, Patricia Balieiro, Alexandre Silva-Neto, Renata Rabello, Marcelo Brito, Emanuelle Silva, Sheila Rodovalho, Ana Ruth Arcanjo, Gisely Melo, Judith Recht, Gonzalo J. Domingo, Suiane Valle, Rodrigo Souza, Theresa Nakagawa, Wuelton Monteiro, Marcus Lacerda   +24 more
doaj   +1 more source

Treatment of knee osteoarthritis with a new formulation of a fixed-dose combination of glucosamine sulfate and bovine chondroitin: a multicenter, randomized, single-blind, non-inferiority clinical trial

Advances in Rheumatology, 2021
Objectives To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patients with knee osteoarthritis (OA ...
Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes, Cristiano Augusto de Freitas Zerbini   +6 more
doaj   +1 more source

Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review

Brazilian Journal of Infectious Diseases, 2014
Background: The natural history of HIV infection has changed dramatically after the introduction of highly active antiretroviral therapy. Currently, opportunistic illnesses still represent a major cause of death and hospitalization in this population. In
Lara Coelho, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Paula Mendes Luz   +3 more
doaj   +1 more source

Pesquisa Clínica e Câncer

Revista Brasileira de Cancerologia, 2021
O primeiro ensaio clínico que se tem ciência data de 600 anos antes da Era comum, com registro no velho testamento, caracterizando-se hoje em dia como um estudo-piloto. A Europa é o continente mais conectado em termos de realização de pesquisa clínica no
Daniel Cohen Goldemberg
doaj   +1 more source

The process of consent in clinical trials: from elaboration to accomplishment [PDF]

, 2005
The consent form is a document recommended for international declarations, resolutions and specific laws currently used in research on health. The practice or the accomplishment of the informed consent in the exercise of the medicine and the research in ...
Muccioli, Cristina [UNIFESP], Oliveira, Filipe de [UNIFESP], Silva, Luci Meire Pereira da [UNIFESP]   +2 more
core   +3 more sources

Uso de Topotecan no tratamento do Tumor Epitelial de Ovário Refratário à Platina: Experiência do INCA

Revista Brasileira de Cancerologia, 2008
Introdução: O câncer de ovário é a principal causa de morte entre os tumores malignos ginecológicos nos Estados Unidos. Apesar dos avanços da terapia inicial, a maioria das pacientes apresentará recaída e necessitará de tratamento adicional.
Luiz Henrique de Lima Araújo, Fernando Meton de Alencar Câmara Vieira, Isabele Ávila Small , Paulo Alexandre Ribeiro Mora, Luciana Camillo Coura , Gustavo Henrique Gomes Advíncula   +5 more
doaj   +1 more source