Results 21 to 30 of about 12,824 (145)

Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review

Brazilian Journal of Infectious Diseases, 2014
Background: The natural history of HIV infection has changed dramatically after the introduction of highly active antiretroviral therapy. Currently, opportunistic illnesses still represent a major cause of death and hospitalization in this population. In
Lara Coelho, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Paula Mendes Luz   +3 more
doaj   +1 more source

Treatment of knee osteoarthritis with a new formulation of a fixed-dose combination of glucosamine sulfate and bovine chondroitin: a multicenter, randomized, single-blind, non-inferiority clinical trial

Advances in Rheumatology, 2021
Objectives To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patients with knee osteoarthritis (OA ...
Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes, Cristiano Augusto de Freitas Zerbini   +6 more
doaj   +1 more source

Pesquisa Clínica e Câncer

Revista Brasileira de Cancerologia, 2021
O primeiro ensaio clínico que se tem ciência data de 600 anos antes da Era comum, com registro no velho testamento, caracterizando-se hoje em dia como um estudo-piloto. A Europa é o continente mais conectado em termos de realização de pesquisa clínica no
Daniel Cohen Goldemberg
doaj   +1 more source

Disrupted genes and pathways in schizophrenia: a robust analysis of the brain and blood

BMC Psychiatry
Background Schizophrenia (SCZ) is a neuropsychiatric disorder that is not yet fully understood, characterized by behavioral, emotional, and cognitive dysfunctions.
Rebeca Rebouças, Mariana Araújo-Pereira, Tiago F. Mota, Henrique Q. S. Scoppetta, Moreno M. S. Rodrigues, Bruno B. Andrade, Eduardo R. Fukutani, Artur Trancoso Lopo de Queiroz   +7 more
doaj   +1 more source

Screening CZE–UV Green Method for Acetate, Propionate, Butyrate, and Valerate Analysis in Human Stool for Complementary Gut Dysbiosis Diagnosis

ELECTROPHORESIS, EarlyView.
A green CZE–UV alternative method for quantifying SCFAs in human stool with cost‐effective and automatization, informative data about patients through reduced sample preparation and minimal consumable. CE is simple and robust equipment for routine clinical laboratory workflows, supporting physicians with information that enhances the accuracy of ...
Olívia B. O. Moreira, Matheus Miranda Fracetti, Eliane B. T. Lemos, Jeanette C. F. Less, Lúcio M. Lemos, Paula Rocha Chellini, Marcone A. L. Oliveira   +6 more
wiley   +1 more source

Uso de Topotecan no tratamento do Tumor Epitelial de Ovário Refratário à Platina: Experiência do INCA

Revista Brasileira de Cancerologia, 2008
Introdução: O câncer de ovário é a principal causa de morte entre os tumores malignos ginecológicos nos Estados Unidos. Apesar dos avanços da terapia inicial, a maioria das pacientes apresentará recaída e necessitará de tratamento adicional.
Luiz Henrique de Lima Araújo, Fernando Meton de Alencar Câmara Vieira, Isabele Ávila Small , Paulo Alexandre Ribeiro Mora, Luciana Camillo Coura , Gustavo Henrique Gomes Advíncula   +5 more
doaj   +1 more source

IDENTIFICAÇÃO DE MARCADORES CELULARES ASSOCIADOS COM IKZF1PLUS EM LEUCEMIA LINFOBLÁSTICA AGUDA DE CÉLULAS PRECURSORAS-B

Hematology, Transfusion and Cell Therapy, 2021
A leucemia linfoblástica aguda de células precursoras B (LLA-CPB) pode ser classificada pela ocorrência de várias alterações genéticas primárias. As alterações de número de cópias (CNAs) em genes relacionados ao desenvolvimento de células-B, como por ...
CB Blunck, CP Poubel, BA Lopes, MB Mansur, M Emerenciano   +4 more
doaj   +1 more source

Irritability in preschool children with attention‐deficit/hyperactivity disorder: Analysis of family environmental factors

JCPP Advances, EarlyView.
Abstract Background Irritability affects one‐third of children and adolescents with attention‐deficit/hyperactivity disorder (ADHD) and is associated with negative outcomes. The family environment plays a prominent role in the child's development, and therefore on the risk for irritability, especially during the preschool period.
Analin Ono Baraniuk, Giovanni Abrahão Salum, David Daley, Erika Mendonça de Morais, Filipe Jaeger Zabala, Luiz Eduardo de Souza, Guilherme V. Polanczyk, Luisa Shiguemi Sugaya   +7 more
wiley   +1 more source

Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To identify risk factors for abdominal pain and predictors of complicated abdominal pain in pediatric immunoglobulin A vasculitis (IgAV). Methods Retrospective multicenter study including children and adolescents (≤18 years) fulfilling the European League Against Rheumatism/Pediatric Rheumatology International Trials Organization ...
Francisco Hugo Rodrigues Gomes, Natalia Maronese, Leticia Lizardo Magalhaes, Davi Casale Aragon, Gleice Clemente, Maria Teresa Terreri, Claudio Arnaldo Len, Rozana Gasparello de Almeida, Marta Cristine Felix Rodrigues, Flavio Sztajnbok, Lia Vineyard Steuer, Matheus Santos França, Clovis Artur Almeida da Silva, Virginia Paes Leme Ferriani, Luciana Martins de Carvalho   +14 more
wiley   +1 more source

An Ultra-Sensitive Technique: Using Pv-mtCOX1 qPCR to Detect Early Recurrences of Plasmodium vivax in Patients in the Brazilian Amazon

Pathogens, 2020
Background: Early recurrence of Plasmodium vivax is a challenge for malaria control in the field, particularly because this species is associated with lower parasitemia, which hinders diagnosis and monitoring through blood smear testing.
Laila R. A. Barbosa, Emanuelle L. da Silva, Anne C. G. de Almeida, Yanka E. A. R. Salazar, André M. Siqueira, Maria das Graças Costa Alecrim, José Luiz Fernandes Vieira, Quique Bassat, Marcus V. G. de Lacerda, Wuelton M. Monteiro, Gisely C. Melo   +10 more
doaj   +1 more source