Results 21 to 30 of about 2,164,601 (194)

Investigações no Campo da Clínica: Notas Sobre as Abordagens Analítico-Comportamental e Fenomenológica

Interação em Psicologia, 2011
O presente artigo se propõe a apresentar considerações sobre as possibilidades e caminhos da investigação clínica fundamentada na Fenomenologia e na Análise Comportamental.
Adriano Furtado Holanda, Jocelaine Martins da Silveira   +1 more
doaj   +1 more source

Health promotion and reduction of vulnerabilities: a strategy for knowledge production and (trans)formation of healthcare work, based on Ergology

Interface: Comunicação, Saúde, Educação, 2010
The present study had the aim of reflecting on the urgency of new possibilities within healthcare settings starting from the proposal to shape an "Extended Community for Health Promotion Research".
Suze Rosa Sant'Ánna, Élida Azevedo Hennington   +1 more
doaj   +1 more source

Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis

Advances in Rheumatology, 2018
Objectives To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose combination of glucosamine hydrochloride and chondroitin sulfate (Cosamin DS®) in capsules
Andrea Barranjard Vannucci Lomonte, José Alexandre Mendonça, Gilberto de Castro Brandão, Marise Lazaretti Castro   +3 more
doaj   +1 more source

A implantação de um serviço de pesquisa clínica em um hospital filantrópico em Curitiba- PR.

Jornal de Assistência Farmacêutica e Farmacoeconomia, 2023
Introdução: O Hospital Universitário Evangélico Mackenzie, um estabelecimento filantrópico de alta complexidade com uma capacidade de 498 leitos, é fortemente dedicado ao atendimento do Sistema Único de Saúde (SUS), representando 91% dos seus pacientes.
Nathalia de Medeiros Santos Tenório Corrêa, Fernanda Carneiro Ronchi, Beatriz Franciele Lorezon Manerich   +2 more
doaj   +1 more source

Filtro de Veia Cava Inferior: Características Clínicas e Prognósticas de Pacientes Oncológicos do INCA

Revista Brasileira de Cancerologia, 2020
Introdução: O tromboembolismo venoso é uma condição potencialmente fatal e frequente no paciente oncológico. Muitas vezes, a anticoagulação é inviável, e a colocação do filtro de veia cava (FVC) torna-se uma opção.
Marcos Jose Pereira Renni, Anke Bergmann, Andreia Cristina de Melo   +2 more
doaj   +1 more source

Functional Restoration of BRCA1 Nonsense Mutations by Aminoglycoside-Induced Readthrough

Frontiers in Pharmacology, 2022
BRCA1 is a major tumor suppressor that functions in the accurate repair of DNA double-strand breaks via homologous recombination (HR). Nonsense mutations in BRCA1 lead to inactive truncated protein products and are associated with high risk of breast and
Renata B. V. Abreu, Thiago T. Gomes, Thales C. Nepomuceno, Thales C. Nepomuceno, Xueli Li, Mateus Fuchshuber-Moraes, Giuliana De Gregoriis, Guilherme Suarez-Kurtz, Alvaro N. A. Monteiro, Marcelo A. Carvalho, Marcelo A. Carvalho   +10 more
doaj   +1 more source

Disrupted genes and pathways in schizophrenia: a robust analysis of the brain and blood

BMC Psychiatry
Background Schizophrenia (SCZ) is a neuropsychiatric disorder that is not yet fully understood, characterized by behavioral, emotional, and cognitive dysfunctions.
Rebeca Rebouças, Mariana Araújo-Pereira, Tiago F. Mota, Henrique Q. S. Scoppetta, Moreno M. S. Rodrigues, Bruno B. Andrade, Eduardo R. Fukutani, Artur Trancoso Lopo de Queiroz   +7 more
doaj   +1 more source

Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review

Brazilian Journal of Infectious Diseases, 2014
Background: The natural history of HIV infection has changed dramatically after the introduction of highly active antiretroviral therapy. Currently, opportunistic illnesses still represent a major cause of death and hospitalization in this population. In
Lara Coelho, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Paula Mendes Luz   +3 more
doaj   +1 more source

Extrapolation and pharmacokinetic protocol design optimization for ceftriaxone as an exemplar for the development of antibiotics for children

British Journal of Clinical Pharmacology, EarlyView.
Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves, Umberto Villani, Salvatore D'Agate, Sean Oosterholt, Ricardo de Carvalho Cavalli, Fabio Carmona, Vera Lucia Lanchote, Oscar Della Pasqua   +7 more
wiley   +1 more source

Treatment of knee osteoarthritis with a new formulation of a fixed-dose combination of glucosamine sulfate and bovine chondroitin: a multicenter, randomized, single-blind, non-inferiority clinical trial

Advances in Rheumatology, 2021
Objectives To compare the efficacy and safety of a new formulation of a fixed dose combination of glucosamine sulfate (GS; 1500 mg) and bovine chondroitin sulfate (CS; 1200 mg) versus the reference product (RP) in patients with knee osteoarthritis (OA ...
Andrea Barranjard Vannucci Lomonte, Emerson Gimenez, Antônio Carlos da Silva, Sebastião Cezar Radominski, Morton Aaron Scheinberg, Antônio Carlos Ximenes, Cristiano Augusto de Freitas Zerbini   +6 more
doaj   +1 more source