Results 91 to 100 of about 389,477 (306)

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia   +8 more
wiley   +1 more source

ECONOMIC ANALYSIS OF ENVIRONMENTAL BENEFITS OF INTEGRATED PEST MANAGEMENT [PDF]

open access: yes
Public support for integrated pest management (IPM) is derived in part from concerns over food safety and the environment, yet few studies have assessed the economic value of health and environmental benefits of IPM.
Mullen, Jeffrey D.   +2 more
core   +1 more source

Dispersal in Mastomys natalensis mice: use of fine-scale genetic analyses for pest management [PDF]

open access: yes, 2008
Mastomys natalensis is the major pest rodent in sub-Saharan Africa. In this study, population genetic techniques were used to gain new insights into its dispersal behaviour, a critical parameter in pest management.
Cosson, J.F.   +3 more
core   +2 more sources

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

open access: yesAdvanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang   +9 more
wiley   +1 more source

BT CORN AND INSECT RESISTANCE: AN ECONOMIC ASSESSMENT OF REFUGES [PDF]

open access: yes
Genetically engineered crops offer farmers a new option for controlling pests. The high efficacy of these pesticidal crops, combined with the potential for widespread adoption, has raised concerns that pest resistance may prematurely diminish their value.
Babcock, Bruce A.   +2 more
core   +1 more source

Prototype of Information System for Horticulture Pest and Disease Distribution [PDF]

open access: yes, 2015
The impact of climate change on the outbreak plant pest and disease seems to be likely increased in the future. However, operational information system on the outbreak of pest and disease on horticulture crops which can provide an overview of outbreak ...
Susanti, E. -. (Erni)
core  

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian   +7 more
wiley   +1 more source

Photonuclear Population of 229m,gTh in Th‐Doped Crystals Toward Nuclear Clock Development

open access: yesAdvanced Science, EarlyView.
This study demonstrates a novel photonuclear approach for producing the nuclear clock isomer 229mTh in thorium‐doped crystals, overcoming current supply limitations. Through cross‐section calculations and Monte Carlo simulations, we identify optimal crystal materials and irradiation conditions, achieving high signal‐to‐noise ratios.
Hao‐Yang Lan   +9 more
wiley   +1 more source

Integrated Pest and Disease Management in Tomato: An Economic Analysis [PDF]

open access: yes
The adoption of IPM technology in tomato using African marigold as a trap crop, root dipping of seedlings in Imidacloprid, soil application of neem/pongamia cake, spraying of botanicals like pongamia soap and biopesticide like Ha NPV has been found ...
Anupama, H.L.   +4 more
core   +1 more source

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