Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia +8 more
wiley +1 more source
Commodity risk assessment of Prunus domestica plants from Ukraine
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH) +34 more
doaj +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
Scientific Opinion on the risk to plant health posed by Phialophora cinerescens (Wollenweber) van Beyma for the EU territory, with the identification and evaluation of risk reduction options [PDF]
The Panel on Plant Health conducted a pest risk assessment for Phialophora cinerescens (Wollenweber) van Beyma (the causal agent of Phialophora carnation wilt) for the EU territory, identified risk management options and evaluated their effectiveness ...
EFSA Panel on Plant Health (PLH)
doaj +1 more source
Photonuclear Population of 229m,gTh in Th‐Doped Crystals Toward Nuclear Clock Development
This study demonstrates a novel photonuclear approach for producing the nuclear clock isomer 229mTh in thorium‐doped crystals, overcoming current supply limitations. Through cross‐section calculations and Monte Carlo simulations, we identify optimal crystal materials and irradiation conditions, achieving high signal‐to‐noise ratios.
Hao‐Yang Lan +9 more
wiley +1 more source
Scientific Opinion on the risk to plant health posed by Parasaissetia nigra (Nietner) in the EU territory, with the identification and evaluation of risk reduction options [PDF]
The Panel on Plant Health conducted a pest risk assessment for Parasaissetia nigra in the European Union (EU) and identified and evaluated the phytosanitary measures listed in Council Directive 2000/29/EC. Entry through the principal pathways is assessed
EFSA Panel on Plant Health (PLH)
doaj +1 more source
QUANTITATIVE PEST RISK ASSESSMENT WITH CAPRA
Methodology of quantitative pest risk assessment developed by 2006 may be applied to CAPRA programme. The way of using this methodology when conducting PRA with CAPRA programme is provided in the paper including assessment of probability of entry of analysed pest to the PRA area, probability of its establishment there and potential economic impact.
openaire +1 more source
Review on the possible interactions of pests, diseases & weeds in cereals grown in organic and conventional agriculture [PDF]
Background The demand for organically produced food is outstripping the ability of UK farmers to supply it and the majority is imported. Furthermore, there is a major shortfall in home-produced organic cereals and cereal products, including straw.
Anon
core
Fibrotic scarring persistently challenges urethral reconstruction. This study introduces a conformal, wearable ultrasound bioelectronic system that overcomes this by reprogramming fibroblast fate. The device activates a developmental Wnt–FGF10 axis, driving fibroblasts toward a regenerative FGF10+ phenotype that promotes angiogenesis and matrix ...
Mingming Yu +7 more
wiley +1 more source
Commodity risk assessment of Taxus baccata plants from the UK
The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’.
EFSA Panel on Plant Health (PLH) +31 more
doaj +1 more source

