Results 61 to 70 of about 13,962 (256)

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

A β-Hairpin Motif in the Envelope Protein E2 Mediates Receptor Binding of Bovine Viral Diarrhea Virus

Viruses, 2021
Pestivirus envelope protein E2 is crucial to virus infection and accomplishes virus-receptor interaction during entry. However, mapping of E2 residues mediating these interactions has remained unexplored.
Fernando Merwaiss, María José Pascual, María Trinidad Pomilio, María Gabriela Lopez, Oscar A. Taboga, Diego E. Alvarez   +5 more
doaj   +1 more source

A Review of Infectious and Non‐Infectious Causes of Pregnancy Loss in Goats

Reproduction in Domestic Animals, Volume 61, Issue 3, March 2026.
ABSTRACT Goats play a vital role in global agriculture, particularly in developing regions, and are increasingly kept as companion animals. Given their economic and social importance, pregnancy losses in goats represent a substantial challenge, leading to considerable economic losses and raising concerns about animal welfare and public health, as some ...
Friederike Maria Kaus, Hannah Eggimann, Barbara Tschulena, Gaby Hirsbrunner, Patrik Zanolari   +4 more
wiley   +1 more source

About the necessity of including HoBi-like pestiviruses in bovine respiratory and reproductive viral vacines

Pesquisa Veterinária Brasileira, 2021
: HoBi-like pestiviruses (HoBiPeV) constitute a novel group of bovine pestiviruses, genetically and antigenically related to bovine viral diarrhea virus 1 (BVDV-1) and BVDV-2.
Paulo Henrique Hümmelgen Silva, Rudi Weiblen, Eduardo F. Flores   +2 more
doaj   +1 more source

Establishment and Evaluation of a Multicolor Latex Microsphere‐Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Jie Chen, Zhengwang Shi, Yi Ru, Juncong Luo, Qianqian Yang, Yage Xie, Lin Wang, Jing Zhou, Xiaoyang Zhang, Juanjuan Wei, Yuqian Zhu, Hong Tian, Haixue Zheng, Nan-hua Chen   +13 more
wiley   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Modulation of ADAM17 Levels by Pestiviruses Is Species-Specific

Viruses
Upon host cell infection, viruses modulate their host cells to better suit their needs, including the downregulation of virus entry receptors. ADAM17, a cell surface sheddase, is an essential factor for infection of bovine cells with several pestiviruses.
Hann-Wei Chen, Marianne Zaruba, Aroosa Dawood, Stefan Düsterhöft, Benjamin Lamp, Till Ruemenapf, Christiane Riedel   +6 more
doaj   +1 more source

New Emergence of the Novel Pestivirus Linda Virus in a Pig Farm in Carinthia, Austria

Viruses, 2022
Linda virus (LindaV) was first identified in a pig farm in Styria, Austria in 2015 and associated with congenital tremor (CT) type A-II in newborn piglets.
Alexandra Kiesler, Lukas Schwarz, Christiane Riedel, Sandra Högler, René Brunthaler, Katharina Dimmel, Angelika Auer, Marianne Zaruba, Marlene Mötz, Kerstin Seitz, Andrea Ladinig, Benjamin Lamp, Till Rümenapf   +12 more
doaj   +1 more source

The control of classical swine fever in wild boar [PDF]

, 2015
Classical swine fever (CSF) is a viral disease with severe economic consequences for domestic pigs. Natural hosts for the CSF virus (CSFV) are members of the family Suidae, i.e. Eurasian wild boar (sus scrofa) are also susceptible. CSF in wild boar poses
Volker Moennig
core   +2 more sources

Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health

Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley   +1 more source