Results 41 to 50 of about 76,163 (331)

Joint Reconstruction via Coupled Bregman Iterations with Applications to PET-MR Imaging

, 2017
Joint reconstruction has recently attracted a lot of attention, especially in the field of medical multi-modality imaging such as PET-MRI. Most of the developed methods rely on the comparison of image gradients, or more precisely their location ...
Brinkmann, Eva-Maria, Burger, Martin, Rasch, Julian   +2 more
core   +1 more source

Reproducibility of Standardized Uptake Values Including Volume Metrics Between TOF-PET-MR and TOF-PET-CT

Frontiers in Medicine, 2022
PurposeTo investigate the reproducibility of tracer uptake measurements, including volume metrics, such as metabolic tumor volume (MTV) and tumor lesion glycolysis (TLG) obtained by TOF-PET-CT and TOF-PET-MR.Materials and MethodsEighty consecutive ...
Aruki Tanaka, Tetsuro Sekine, Tetsuro Sekine, Tetsuro Sekine, Tetsuro Sekine, Edwin E. G. W. ter Voert, Edwin E. G. W. ter Voert, Konstantinos G. Zeimpekis, Konstantinos G. Zeimpekis, Konstantinos G. Zeimpekis, Gaspar Delso, Felipe de Galiza Barbosa, Felipe de Galiza Barbosa, Geoffrey Warnock, Geoffrey Warnock, Geoffrey Warnock, Shin-ichiro Kumita, Patrick Veit Haibach, Patrick Veit Haibach, Patrick Veit Haibach, Patrick Veit Haibach, Martin Huellner, Martin Huellner   +22 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Markerless attenuation correction for carotid MRI surface receiver coils in combined PET/MR imaging. [PDF]

, 2015
The purpose of the study was to evaluate the effect of attenuation of MR coils on quantitative carotid PET/MR exams. Additionally, an automated attenuation correction method for flexible carotid MR coils was developed and evaluated.The attenuation of the
Bini, J, Calcagno, C, Eldib, M, Faul, DD, Fayad, ZA, Robson, PM, Tsoumpas, C   +6 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Reproducibility of Quantitative Brain Imaging Using a PET-Only and a Combined PET/MR System

Frontiers in Neuroscience, 2017
The purpose of this study was to test the feasibility of migrating a quantitative brain imaging protocol from a positron emission tomography (PET)-only system to an integrated PET/MR system.
Martin L. Lassen, Otto Muzik, Thomas Beyer, Marcus Hacker, Claes Nøhr Ladefoged, Jacobo Cal-González, Wolfgang Wadsak, Wolfgang Wadsak, Ivo Rausch, Oliver Langer, Oliver Langer, Oliver Langer, Martin Bauer   +12 more
doaj   +1 more source

Initial Measurements with the PETsys TOFPET2 ASIC Evaluation Kit and a Characterization of the ASIC TDC

, 2018
For a first characterization, we used the two KETEK-PM3325-WB SiPMs each equipped with a 3x3x5 mm${}^3$ LYSO scintillation crystal provided with the PETsys TOFPET2 ASIC Evaluation Kit.
Gebhardt, Pierre, Nadig, Vanessa, Schug, David, Schulz, Volkmar, Weissler, Bjoern   +4 more
core   +1 more source

Simultaneous in vivo positron emission tomography and magnetic resonance imaging [PDF]

, 2008
Positron emission tomography (PET) and magnetic resonance imaging (MRI) are widely used in vivo imaging technologies with both clinical and biomedical research applications.
Catana, Ciprian, Cherry, Simon R., Jacobs, Russell E., Judenhofer, Martin S., Pichler, Bernd J., Procissi, Daniel, Qi, Jinyi, Wu, Yibao   +7 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source