Results 51 to 60 of about 1,069,547 (329)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions [PDF]

, 2015
The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities.
Al-Yassiry, M.M., Al-Yassiry, Mustafa M., Archibald, S.J., Archibald, Stephen J., Baghdadi, N., Baghdadi, Neazar, Burke, B.P., Burke, Benjamin P., Cawthorne, Christopher, Clemente, G.S., Clemente, Goncalo S., Clemente, Gonçalo S., Domarkas, Juozas, Gibbs, P., Gibbs, Peter, Kownacka, Alicja E., Lorch, Mark, Nigam, S., Nigam, Shubhanchi, Pickles, M., Pickles, Martin, Tripier, R., Tripier, Raphael, Tripier, Raphaël   +23 more
core   +2 more sources

Radiomics Analysis and Correlation With Metabolic Parameters in Nasopharyngeal Carcinoma Based on PET/MR Imaging

Frontiers in Oncology, 2020
Objective: Accurate staging is of great importance in treatment selection for patients with nasopharyngeal carcinoma (NPC). The aims of this study were to construct radiomic models of NPC staging based on positron emission tomography (PET) and magnetic ...
Qi Feng, Jiangtao Liang, Luoyu Wang, Jialing Niu, X. Ge, P. Pang, Z. Ding   +6 more
semanticscholar   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Initial Measurements with the PETsys TOFPET2 ASIC Evaluation Kit and a Characterization of the ASIC TDC

, 2018
For a first characterization, we used the two KETEK-PM3325-WB SiPMs each equipped with a 3x3x5 mm${}^3$ LYSO scintillation crystal provided with the PETsys TOFPET2 ASIC Evaluation Kit.
Gebhardt, Pierre, Nadig, Vanessa, Schug, David, Schulz, Volkmar, Weissler, Bjoern   +4 more
core   +1 more source

Markerless attenuation correction for carotid MRI surface receiver coils in combined PET/MR imaging. [PDF]

, 2015
The purpose of the study was to evaluate the effect of attenuation of MR coils on quantitative carotid PET/MR exams. Additionally, an automated attenuation correction method for flexible carotid MR coils was developed and evaluated.The attenuation of the
Bini, J, Calcagno, C, Eldib, M, Faul, DD, Fayad, ZA, Robson, PM, Tsoumpas, C   +6 more
core   +1 more source

Reproducibility and repeatability of same-day two sequential FDG PET/MR and PET/CT

Cancer Imaging, 2017
Background To determine PET/CT and PET/MR reproducibility and PET/MR repeatability of fluorine 18 fluorodeoxyglucose (FDG) uptake measurements in tumors in cancer patients.
David Groshar, Hanna Bernstine, Natalia Goldberg, Meital Nidam, Dan Stein, Ifat Abadi-Korek, Liran Domachevsky   +6 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Simultaneous in vivo positron emission tomography and magnetic resonance imaging [PDF]

, 2008
Positron emission tomography (PET) and magnetic resonance imaging (MRI) are widely used in vivo imaging technologies with both clinical and biomedical research applications.
Catana, Ciprian, Cherry, Simon R., Jacobs, Russell E., Judenhofer, Martin S., Pichler, Bernd J., Procissi, Daniel, Qi, Jinyi, Wu, Yibao   +7 more
core   +2 more sources