Results 301 to 310 of about 528,168 (327)
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2019
The deposition of fibrillar tau aggregates has been implicated in Alzheimer's disease (AD) and allied neurodegenerative disorders collectively referred to as tauopathies. Growing non-clinical and clinical evidence has supported intimate links between tau fibrillogenesis and neuronal deteriorations, rationalizing the development of imaging agents for ...
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The deposition of fibrillar tau aggregates has been implicated in Alzheimer's disease (AD) and allied neurodegenerative disorders collectively referred to as tauopathies. Growing non-clinical and clinical evidence has supported intimate links between tau fibrillogenesis and neuronal deteriorations, rationalizing the development of imaging agents for ...
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2014
Multimodalbrain imaging has become an established clinical and research tool for diagnosis and disease progression of brain disorders. Among available imaging modalities, magnetic resonance imaging (MRI) and positron emission tomography (PET) can provide a wide spectrum of data for the in vivo mapping of neurobiological functions and brain morphology ...
Koole, M. +4 more
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Multimodalbrain imaging has become an established clinical and research tool for diagnosis and disease progression of brain disorders. Among available imaging modalities, magnetic resonance imaging (MRI) and positron emission tomography (PET) can provide a wide spectrum of data for the in vivo mapping of neurobiological functions and brain morphology ...
Koole, M. +4 more
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PET Imaging of Atherosclerosis
Future Cardiology, 2015Atherosclerosis is a chronic, progressive, multifocal disease of the arterial wall, which is mainly fuelled by local and systemic inflammation, often resulting in acute ischemic events following plaque rupture and vessel occlusion. When assessing the cardiovascular risk of an individual patient, we must consider both global measures of disease activity
Jason M, Tarkin +3 more
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Neuroimaging Clinics of North America
Following a brief review of brain neurofluid pathways and the general PET technique, we introduce PET imaging of cerebrospinal fluid and interstitial fluid dynamics. Our summary includes both our published and unpublished observations on the modeling of PET imaging for neurofluid quantification in aging, Alzheimer's disease, and in the presence of ...
Liangdong, Zhou, Yi, Li, Mony J, de Leon
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Following a brief review of brain neurofluid pathways and the general PET technique, we introduce PET imaging of cerebrospinal fluid and interstitial fluid dynamics. Our summary includes both our published and unpublished observations on the modeling of PET imaging for neurofluid quantification in aging, Alzheimer's disease, and in the presence of ...
Liangdong, Zhou, Yi, Li, Mony J, de Leon
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Orthopedic Clinics of North America, 2015
PET imaging has been evaluated in five areas of sarcoma diagnosis and treatment: biopsy guidance, therapeutic monitoring, tumor detection and grading, tumor staging, and prognostication. Current evidence does not include any cost-benefit analysis showing a decreased number of invasive procedures from false-positive results.
Stephen, Becher, Shervin, Oskouei
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PET imaging has been evaluated in five areas of sarcoma diagnosis and treatment: biopsy guidance, therapeutic monitoring, tumor detection and grading, tumor staging, and prognostication. Current evidence does not include any cost-benefit analysis showing a decreased number of invasive procedures from false-positive results.
Stephen, Becher, Shervin, Oskouei
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Expert Review of Hematology, 2009
PET has become a cornerstone procedure in modern lymphoma management. This paper reviews, from a clinical point of view, the evidence for using PET in the different subtypes of lymphoma and the different steps of their management. The reader is given an overview of the current PET-based interventional lymphoma trials and an insight into possible future
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PET has become a cornerstone procedure in modern lymphoma management. This paper reviews, from a clinical point of view, the evidence for using PET in the different subtypes of lymphoma and the different steps of their management. The reader is given an overview of the current PET-based interventional lymphoma trials and an insight into possible future
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European Journal of Nuclear Medicine and Molecular Imaging, 2007
There is growing evidence that myocardial metabolism plays a key role not only in ischaemic heart disease but also in a variety of diseases which involve myocardium globally, such as heart failure and diabetes mellitus. Understanding myocardial metabolism in such diseases helps to elucidate the pathophysiology and assists in making therapeutic ...
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There is growing evidence that myocardial metabolism plays a key role not only in ischaemic heart disease but also in a variety of diseases which involve myocardium globally, such as heart failure and diabetes mellitus. Understanding myocardial metabolism in such diseases helps to elucidate the pathophysiology and assists in making therapeutic ...
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PET Imaging of Pheochromocytoma
PET Clinics, 2007Pheochromocytomas are tumors derived from chromaffin cells of the adrenal medulla that synthesize, store, metabolize, and usually, but not always, secrete catecholamines. Although pheochromocytomas are the cause of hypertension in only a small number of patients, they can precipitate life-threatening hypertension or cardiac arrhythmias caused by ...
Sameer, Khan +6 more
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Applications of Small Animal Imaging with PET, PET/CT, and PET/MR Imaging
PET Clinics, 2008Small animal techniques of PET, MR imaging, and CT are most frequently applied in preclinical oncology research, but cardiovascular and neurologic research protocols can also take advantage of these innovative approaches. PET is used to provide functional information about disease activity.
Cristina, Nanni, Drew A, Torigian
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PET Imaging in Neuroinflammation
2014The presence of microglial activation in the brain provides a marker of disease activity. The function of activated microglia can be both detrimental and beneficial depending on the phenotype. Microglia with the M1 phenotype release cytokines, which may drive disease progression, while M2 microglia generate restorative growth factors, help clear ...
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