Results 131 to 140 of about 87,496 (253)

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Diagnosis of Cancer Disease with High Accuracy via Petri Net Modeling of Signaling Pathways

Abstract Cancer remains a leading cause of death worldwide, affecting millions of people each year. There are many different types of cancer, including breast cancer, colon cancer and endometrial cancer, each with its own unique characteristics and challenges. One of the most crucial aspects of cancer management is early detection.
Sima Khodaei, Mohsen Sarvari, Ehsan Sajadi, Fatemeh Assadzadeh, Hananeh Ebrahimian, Maseud Rahgozar, Kaveh Kavousi   +6 more
openaire   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

Cytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

Chromoblastomycosis caused by <i>Fonsecaea pedrosoi</i>: a case report and literature review. [PDF]

Front Med (Lausanne)
Wang Y, Wang L, Li Z, Qu Y, Liu Y.
europepmc   +1 more source

Characterization and pathogenicity of Phaeoacremoniun species associated with Petri disease and esca of grapevines in Spain

, 2017
Trabajo presentado en el 10th International Workshop on Grapevine Trunk Diseases, celebrado en Reims (Francia), del 4 al 7 de julio de ...
Berlanas, Carmen, Pečenka, Jakub, López-Manzanares, Beatriz, Armengol, Josep, Gramaje, David   +4 more
openaire   +1 more source

Double Sided Traction Force Microscopy: A Method to Confine Cells for Physiologically Relevant Force Measurements

Cytoskeleton, EarlyView.
ABSTRACT In this paper we describe a technique to make a confined environment of variable stiffness that is suitable for high‐resolution live‐cell imaging. This versatile and adaptable technique enables cell confinement between soft elastic surfaces made from polyacrylamide gels.
Alexia Caillier, Patrick W. Oakes
wiley   +1 more source

Editorial: Safety and efficacy of CRISPR/Cas-based genome editing tools: applications and considerations in cell and gene therapy. [PDF]

Front Immunol
Petri K, Ferrari S, Cianciotti BC.
europepmc   +1 more source

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

Equine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas, T. A. E. Stout, J. C. M. Vernooij, B. Leemans, L. Arnold, M. M. Beitsma, L. I. Wijnands, M. de Ruijter‐Villani, S. Colleoni, G. Lazzari, C. Galli, A. Claes   +11 more
wiley   +1 more source

Endophytic Trichoderma and Bacillus isolates suppress Lasiodiplodia theobromae-associated dieback in blueberry under arid coastal conditions. [PDF]

Sci Rep
Villanueva-Olivera W, Valladolid-Suyón E, Palomino M, Paredes J JC, Rivas J, Solórzano R, Jaramillo-Carrión M.   +6 more
europepmc   +1 more source