Results 91 to 100 of about 29,350 (298)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch   +13 more
wiley   +1 more source

Time Management Approach on a Discrete Event Manufacturing System Modeled by Petri Net

open access: yesInternational Journal of Industrial Engineering and Production Research, 2011
Discrete event system,   Supervisory control,   Petri Net, Constraint   This paper presents a method to manage the time in a manufacturing system for obtaining an optimized model.
Meysam Zareiee   +2 more
doaj  

Designing Traffic Light Signals to Ease Congestion Caused by Traffic Accidents Using Timed Petri Net

open access: yesApplied Sciences
This study develops a timed Petri net (TPN)-based controller to mitigate traffic congestion resulting from sudden accidents by adapting traffic light sequences in real-time.
Ter-Chan Row   +2 more
doaj   +1 more source

Shape‐Changing Multiphase Microparticles from Complex Liquid Crystal Emulsions

open access: yesAdvanced Functional Materials, EarlyView.
Liquid crystalline network (LCN) microparticles are prepared from single, double (Janus), and triple emulsions through a simple and scalable bulk‐emulsification strategy. Under heating, the particles exhibit robust, reversible, large‐amplitude deformations that depend both on the morphology and the liquid crystals director field configuration.
Marco Turriani   +3 more
wiley   +1 more source

Attacks and Defenses in Mobile IP: Modeling with Stochastic Game Petri\n Net [PDF]

open access: green, 2018
Sajedul Talukder   +4 more
openalex   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng   +16 more
wiley   +1 more source

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