Results 191 to 200 of about 168,423 (268)

A Simulation Study of a Novel Electrokinetic-Based Focusing Technique to Enhance the Real-Time Detection of Microplastics in Water Flow. [PDF]

Sensors (Basel)
Abdulhameed A, Mahnashi Y.
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

A stable solid-like water at normal condition. [PDF]

Sci Rep
Wei-Qing A, Xiang-An Y, Ji-Rui Z.
europepmc   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Metabolic Specialization and Synergy in Alkane Degradation By a Microbial Consortium: An Integrated Genomic and Geochemical Approach. [PDF]

Curr Microbiol
de Santana Nazaré PGB, de Menezes Neto AA, de Oliveira LA, de Souza Queiroz AF, de Oliveira OMC, Lima DF.   +5 more
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Konjac petroleum ether extract inhibits triple-negative breast cancer cell migration and invasion by attenuating <i>OLFML2A</i>-mediated epithelial-mesenchymal transition. [PDF]

Front Pharmacol
Chen Y, Yu Q, Ding H, Jiang W, Gao X.
europepmc   +1 more source

Resolving and Controlling Silicoaluminophosphate Zeolite Intergrowths and Mixtures

Advanced Science, EarlyView.
Low‐dose electron microscopy enables atomic‐resolution imaging of beam‐sensitive SAPO‐34/18 intergrowths, revealing their stacking sequences and spatial distributions under controlled Si content and SDA ratio. This work establishes a methodology linking controllable synthesis with atomic‐resolution microscopy to investigate structure–property ...
Yuxin Ke, Jiale Feng, Lei Wang, Xiao Chen, Mengmeng Ma, Jiabin Cui, Juan Diwu, Yuman Liu, Fei Wei, Boyuan Shen, Bin Song   +10 more
wiley   +1 more source

Rotary cutting tests and rock-breaking characteristics of triple-ridged PDC cutters in tight hard sandstones from Xujiahe Formation in Sichuan Basin in China. [PDF]

Sci Rep
He W, Li X, Zhang Z, Shi H, Chen H, Ma Q, Huang Z, Xiong C, Dong J, Li Y.   +9 more
europepmc   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source