Results 171 to 180 of about 402,888 (305)

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Retraction: Environmental dust removal from inclined hydrophobic glass surface: avalanche influence on dynamics of dust particles. [PDF]

RSC Adv
Yilbas BS, Al-Sharafi A, Ali H, Al-Aqeeli N, Al-Qahtani H, Al-Sulaiman F, Abu-Dheir N, Abdelmagid G, Elkhazraji A.   +8 more
europepmc   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

Advanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang, Jiayi Xu, Liang Ran, Xinhe Feng, Khalil Harrabi, Yida Li, Longyang Lin, Feichi Zhou   +7 more
wiley   +1 more source

Retraction: Water droplet on inclined dusty hydrophobic surface: influence of droplet volume on environmental dust particles removal. [PDF]

RSC Adv
Hassan G, Yilbas BS, Al-Sharafi A, Al-Qahtani H, Al-Aqeeli N.   +4 more
europepmc   +1 more source

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

Advanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo, Subramanya Hegde, Xuan Jia, Kimberly Coffman, Hariprasad Vankayalapati, David Bearss, Kevin B. Jones, Alex W. Stark, Peter S. Shen   +8 more
wiley   +1 more source

Advances in petroleum storage and transportation engineering

Advances in Mechanical Engineering, 2015
Bo Yu, Yuxing Li, Xiaoyan Liu, Paulo R de Souza Mendes, John C Chai, Shuyu Sun   +5 more
doaj   +1 more source

Retraction: Dynamics of a water droplet on a hydrophobic inclined surface: influence of droplet size and surface inclination angle on droplet rolling. [PDF]

RSC Adv
Yilbas BS, Al-Sharafi A, Ali H, Al-Aqeeli N.   +3 more
europepmc   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

Retraction: Droplet fluid infusion into a dust layer in relation to self-cleaning. [PDF]

RSC Adv
Hassan G, Yilbas BS, Al-Qahtani H.
europepmc   +1 more source

Valuing Oil & Gas Properties [PDF]

, 2000
McGowen, Robert M.
core   +2 more sources