Results 21 to 30 of about 5,885,903 (302)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Optimization of the transition timing from natural flow to artificial lift in Jimusar shale oil wells

open access: yesShenzhen Daxue xuebao. Ligong ban
To mitigate the matrix stress-sensitive damage induced by gradual reservoir pressure depletion during the late production stage of shale oil wells, and to optimize the post-fracturing development strategy for horizontal wells transitioning from natural ...
ZHU Jian, WANG Fei
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Identification of Reservoir Flow Zone & Permeability Estimation: Review Paper

open access: yesEgyptian Journal of Petroleum
Reservoir flow zonation is essential in evaluating heterogeneity reservoirs, constructing static/dynamic models, and reserve calculations in any reservoir characteristic.
Alaa S. Al-Rikaby   +1 more
doaj   +1 more source

Application of temperature-dependent adsorption models in material balance calculations for unconventional gas reservoirs

open access: yesHeliyon, 2019
Langmuir isotherm is the most common adsorption model used in the prediction of gas adsorption in most shale and coal bed methane reservoirs. However, due to the underlying assumption of single temperature, it fails to model gas adsorption where ...
John Fianu   +2 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

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