Results 101 to 110 of about 38,240 (262)

Insight in the phenomena included in loss of the activation of industrial hydrotreating catalyst through an innovative accelerated deactivation procedure and kinetic modeling

Fuel Processing Technology
An innovative accelerated experimental procedure was developed to study the activity loss of a bifunctional gasoil hydrotreating (GHT) catalyst in a Bench-Scale fixed bed reactor system.
Abbas Roshanaei, Sorood Zahedi Abghari, Sepehr Sadighi, Seyed Reza Seif Mohaddecy   +3 more
doaj   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Effects of salinity on the treatment of synthetic petroleum-industry wastewater in pilot vertical flow constructed wetlands under simulated hot arid climatic conditions. [PDF]

Environ Sci Pollut Res Int, 2021
Wagner TV, Al-Manji F, Xue J, Wetser K, de Wilde V, Parsons JR, Rijnaarts HHM, Langenhoff AAM.   +7 more
europepmc   +1 more source

Metal‐Support Interaction Triggered Electronic Reconstruction in Pd/CoN‐Co4N Catalysts for Optimizing MEK Oxidation and Poisoning Resistance

Advanced Science, EarlyView.
The strengthened EMSI in Pd/CoN‐Co4N induces electronic rearrangement, generating abundant Pd0 species in situ, modulating the Pd d‐band center to enhance O2 adsorption and MEK activation. Concurrently, it creates numerous Lewis acid sites that preferentially adsorb poisons and shield the active sites.
Yadi Wang, Chaoqian Ai, Cai Wang, Zeyu Jiang, Jialei Wan, Jingjing Wang, Xiangbo Feng, Chi He   +7 more
wiley   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Evaluation of rock and fluid intermolecular interaction between asphaltene and sand minerals using electrochemical, analytical spectroscopy and microscopy techniques

Scientific Reports
Long-time contact of heavy crude oil with rock leads to an adsorption phenomenon, which causes the rock surface to become oil-wet and appears as a barrier to the fluid flow in the porous media.
Jaber Taheri-Shakib, Ali Esfandiarian, Mahyar Rajabi-Kochi, Ezzatallah Kazemzadeh, Mohammad Afkhami Karaei   +4 more
doaj   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Thermodynamic analysis and intelligent modeling of statin drugs solubility in supercritical carbon dioxide

Scientific Reports
Evaluating the solubility of various drugs in supercritical CO2 is a fundamental step in developing a supercritical process for formulating new pharmaceuticals.
Mitra Amani, Abbas Shahrabadi, Nedasadat Saadati Ardestani   +2 more
doaj   +1 more source

Inflection point: The future of subcontracting in the petroleum industry. [PDF]

Transp Res Interdiscip Perspect, 2020
Tupaz JCVC.
europepmc   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source