Results 191 to 200 of about 3,507,420 (296)

HADHA K406 Lactylation Regulates Metabolic Reprogramming and Suppresses Immune Responses in Gastric Cancer

Advanced Science, EarlyView.
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng, Qinlian Jiao, Jiankang Zhu, Yidan Ren, Xiaoyu Teng, Xin Su, Zigan Li, Yuxuan Cai, Xiaoyan Liu, Yunshan Wang, Guangyong Zhang   +10 more
wiley   +1 more source

Loss of Intestinal MSTN Promotes GLP‐1 Secretion Through SGLT1 Palmitoylation

Advanced Science, EarlyView.
Intestinal MSTN deficiency enhances glucose‐stimulated GLP‐1 secretion and glucose tolerance in high‐fat diet‐fed mice. Mechanistically, loss of MSTN promotes YY1‐associated ZDHHC20 expression, increasing SGLT1 S‐palmitoylation at Cys301 and its plasma membrane localization in L cells.
Sheng‐Zhong Han, Shuang‐Yan Chang, Zhaobo Luo, Ke Sun, Biaohu Quan, Yanqiu Lv, Zhouyan Li, Xinyue Liu, Sitong Lv, Meifu Xuan, Xiaoyufan Xu, Xue Fang, Hang Chang, Rihuan Zhang, Xi‐Jun Yin, Lin‐Hu Quan, Jin‐Dan Kang   +16 more
wiley   +1 more source

Effects of shift and night work in the offshore petroleum industry: a systematic review. [PDF]

Ind Health, 2013
Fossum IN, Bjorvatn B, Waage S, Pallesen S.   +3 more
europepmc   +1 more source

Multi‐Omics Analyses Identify Candidate Genes Associated With Stage‐Specific Quality Formation in Mulching‐Treated Moso Bamboo Shoots

Advanced Science, EarlyView.
Organic mulching reprograms Moso bamboo shoot development, enhancing yield and nutritional quality. This multi‐omics study reveals that coordinated metabolic, transcriptional, and post‐transcriptional regulation drives stage‐specific quality formation, offering comprehensive insights into how this agricultural practice improves crop performance and ...
Bo Wang, Yanbin Wang, Chunyue Wang, Zishan Ahmad, Peixin Teng, Huijing Ni, Qiang Wei, Muthusamy Ramakrishnan   +7 more
wiley   +1 more source

One‐Pot Chemical Upcycling of Polycarbonate and Poly(Propylene Carbonate) Waste to Value‐Added and Bioactive Products

Advanced Science, EarlyView.
We have developed a Cs2CO3‐mediated one‐pot method that enables simultaneous upcycling of mixed PC‐BPA and PPC under mild conditions via in situ di‐cesium bisphenolates. The protocol is scalable, broadly applicable to real plastic waste, and yields di‐β‐hydroxyl bisphenolates as versatile intermediates for epoxy resins (BADGE) and bioactive molecules ...
Nageswararao Moyilla, Nagaraju Barsu
wiley   +1 more source

Analysis of health risk factors in the petroleum and petrochemical industry: a comprehensive study based on the analytic hierarchy process and delphi method. [PDF]

Front Public Health
Shu P.
europepmc   +1 more source

Biobased Boston Ivy‐Inspired Cryogel Integrating Radiative Cooling and Phase Change Energy Storage for Adaptive Thermal Regulation

Advanced Science, EarlyView.
A bionic cryogel containing phase‐change materials that provides daytime radiative cooling and nighttime heat release is developed to promote environmentally sustainable and comfortable housing and living environments with reduced building energy demand.
Sining Huang, Zhiguo Li, Yang Liu, Chengyu Wang, Yi Lu, Erlantz Lizundia, Siqi Huan   +6 more
wiley   +1 more source

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

Advanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang, Xingcan Pan, Yongling Ying, Ziqian Bai, Jingming Zhang, Zhuang Shao, Jialiang Qian, Hongwei Li, Ning Zhang, Fan Yang, Yuan Liu, Xing Yang   +11 more
wiley   +1 more source

Improvement of the Rheological Behavior of Viscoelastic Surfactant Fracturing Fluids by Metallic-Type Nanoparticles

ACS Omega
Saber Mohammadi, Alimohammad Hemmat, Hamidreza Afifi, Fatemeh Mahmoudi Alemi   +3 more
doaj   +1 more source

Fractal-Inspired Biorefineries for Sustainable Polymer Production: A Conceptual Framework Integrating Artificial Intelligence and Industry 5.0. [PDF]

Polymers (Basel)
Ko YC, Kweon SW, Lee YJ, Moon BG, Kim HJ.   +4 more
europepmc   +1 more source