Results 211 to 220 of about 87,223 (311)

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Investigation into the Enhancement Effects of Combined Bioremediation of Petroleum-Contaminated Soil Utilizing Immobilized Microbial Consortium and Sudan Grass. [PDF]

Toxics
Wang TJ, Ding ZY, Hua ZW, Yuan ZW, Niu QH, Zhang H.   +5 more
europepmc   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

Advanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu   +3 more
wiley   +1 more source

Aquathermolytic Upgrading of Zarafshanian Extra Heavy Oil Using Ammonium Alum. [PDF]

Molecules
Ali Akhunov A, Aliev F, Mukhamadiev N, Kahwir OF, Dengaev A, Majeed MY, Esmaeel M, Al-Qaz A, Mirzaev O, Vakhin A.   +9 more
europepmc   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Gas-Water Two-Phase Flow Mechanisms in Deep Tight Gas Reservoirs: Insights from Nanofluidics. [PDF]

Nanomaterials (Basel)
Pei X, Dai L, Wang C, Zhong J, Ren X, Wang Z, Peng C, Zhang Q, Zhang N.   +8 more
europepmc   +1 more source

Gram‐Scale Synthesis of Hafnium‐Rich Carbon Dots for Preclinical Computed Tomography Imaging Across Various Systems

Advanced Science, EarlyView.
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li, Hengrui Wu, Jianqi Deng, Qiyu Sun, Yuping Zhang, Cai Zhang, Jinbin Pan, Dingbin Liu, Xuejun Zhang, Quan Zou, Xiaoyuan Chen, Shao‐Kai Sun   +11 more
wiley   +1 more source

Monitoring the Biodegradation Progress of Naphthenic Acids in the Presence of <i>Spirulina platensis</i> Algae. [PDF]

Toxics
Gheorghe CG, Dusescu-Vasile CM, Popovici DR, Bombos D, Dragomir RE, Dima FM, Bajan M, Vasilievici G.   +7 more
europepmc   +1 more source

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

Advanced Science, EarlyView.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang, Shitao Dou, Yifan Wu, Mingguang Wang, Taibin Wu   +4 more
wiley   +1 more source

Sustainable alkane production from waste fatty acids via electrochemically coupled decarboxylation and hydrogenation. [PDF]

Nat Commun
Wei W, Wei Z, Luo X, Yuan H, Zhou Q, Ren X, Ouyang S, Zhang T, Ma D.   +8 more
europepmc   +1 more source