Results 221 to 230 of about 591,025 (333)

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

open access: yesAdvanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao   +11 more
wiley   +1 more source

Dual‐Wavelength Responsive Hydrogel Glue with Visible‐Light Bonding and UV‐Triggered Debonding via Ortho‐Nitrobenzyl Cleavage

open access: yesAdvanced Science, EarlyView.
A dual‐wavelength responsive hydrogel glue achieves orthogonal control of bonding and debonding: visible light drives crosslinking via acrylic acid, while ortho‐nitrobenzyl (ONB) units enable rapid UV‐triggered network cleavage. This smart adhesive offers strong adhesion, fast on‐demand debonding, and spatiotemporal precision for potential applications
Huaming Wang   +9 more
wiley   +1 more source

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim   +7 more
wiley   +1 more source

Present Development of Petroleum Refining

open access: yesBulletin of The Japan Petroleum Institute, 1960
openaire   +2 more sources

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