Results 71 to 80 of about 86,361 (303)
Histopathological Study of Canine Skin Hemangiomas and Hemangiosarcomas in Uruguay
PetsWe performed an histological study on all cases of canine skin hemangiomas and hemangiosarcomas that were examined between 2018 and 2020. Of the 446 dogs with skin tumors examined, 25 were diagnosed with hemangiomas and 24 were diagnosed with ...
Belén Varela +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
PetsThis study aimed to obtain information on veterinarians’ experience regarding the management of diabetes mellitus (DM) in the United Kingdom and Europe.
Tereza Jaresova +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
PetsDogs, especially as pets but also an increasing number of stray dogs, share environments with humans, facilitating the transfer of antibiotic resistance genes (ARGs) between genetic compartments, with zoonotic and public health implications that must be ...
María Daniela Frade-Pérez +7 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Double Tooth in a Dog: A Case Report and Treatment of a Developmental Tooth Disorder
PetsTooth structure anomalies, though not frequently described, can be observed in the external appearance not only of humans but also of dogs. The emergence of an oversized set of teeth is not solely an esthetic and health problem, but often also leads to ...
Anna Misztal-Kunecka, Stanisław Dzimira
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Clinical Characteristics and Surgical Outcomes of Suspected Congenital Type II Phimosis in Two Cats
PetsPhimosis is rarely reported in cats and involves the inability to exteriorize the penis through an absent or abnormally narrowed preputial orifice.
Vassiliki Tsioli +5 more
doaj +1 more source