Results 101 to 110 of about 9,065,234 (263)

Inhibition of phosphodiesterases 1 and 4 prevents myofibroblast transformation in Peyronie's disease

open access: yesBJU International, Volume 135, Issue 5, Page 810-817, May 2025.
Objectives To investigate which phosphodiesterase (PDE) isoforms are expressed in fibroblasts isolated from the tunica albuginea (TA) of patients with Peyronie's disease (PD), and to measure the potency of PDE inhibitors in preventing transformation of these fibroblasts to profibrotic myofibroblasts.
Sophie L. Harding   +4 more
wiley   +1 more source

Verteporfin as a Medical Treatment in Peyronie’s Disease

open access: yesSexual Medicine, 2018
Introduction: In Europe and the United States, verteporfin (Visudyne; VP) is registered and used in treating macular degeneration. Research showed that VP decreased expression of fibrotic genes in fibroblasts collected from nodules of patients suffering ...
Daan C.J. Mohede, MD   +3 more
doaj   +1 more source

Current insights and future directions in Peyronie's disease management: A narrative review

open access: yesUroPrecision, Volume 3, Issue 1, Page 3-16, March 2025.
Abstract Peyronie's disease (PD) is an inflammatory and fibrotic disease which results in disfiguring and often distressing penile curvature deformity, affecting up to one in nine men in the United States, and between 0.3% and 13.1% of men globally. It progresses through an acute phase, associated with pain, as the fibrosis develops.
Skyler Howell   +2 more
wiley   +1 more source

Glomus tumor of penis- A rare case [PDF]

open access: yes, 2013
Glomus tumors are rare, painful, and benign soft tissue tumors of the skin arising from the glomus body, an arteriovenous thermoregulatory structure. This lesion is usually found on the extremities.
Madhuri S. Kate   +2 more
core  

An example of genre shift in the medicinal product information genre system [PDF]

open access: yes, 2012
Medical writers and translators need information of three kinds: conceptual, contextual and textual. When in possession of this information, they can progressively improve their efficiency. Textual genre has proved to be useful to linguistic mediators of
Ezpeleta-Piorno, Pilar
core   +1 more source

Prevalence of Peyronie and Ledderhose Diseases in a Series of 730 Patients with Dupuytren Disease [PDF]

open access: yes, 2020
BACKGROUND: Dupuytren, Peyronie, and Ledderhose diseases are related fibroproliferative disorders characterized by abnormalities in the connective tissue of the palm of the hand, the tunica albuginea of the penis, and the sole of the foot, respectively ...
de Jong, Igle Jan   +4 more
core   +1 more source

Penile Metastasis as the Presenting Symptom of Colorectal Carcinoma: A Rare Case Report

open access: yesCase Reports in Urology, Volume 2025, Issue 1, 2025.
Background: Secondary penile cancer, despite the region’s rich vascularization, is a rare phenomenon with only around 500 cases ever reported, typically of genitourinary origin and in even rarer cases, of colorectal adenocarcinoma. Unfortunately, the underlying mechanisms are not well elucidated, and prognosis remains poor with a late onset and median ...
Mann Patel   +5 more
wiley   +1 more source

Inner Preputial Flap as Tunica Albuginea Replacement in The Management of Previously [PDF]

open access: yes, 2010
 Objectives: To assess the efficacy of an inner preputial skin flap as replacement for the tunica albuginea of the corpus cavernosum after excision of fibrous plaque. Patients and Methods: In this retrospective study we evaluated 5 men who presented with
Bhat, A, Dawan, M, Saxena, G, Sharma, B
core   +2 more sources

Extracorporeal Shock Wave Therapy in Peyronie's Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

open access: yesThe World Journal of Men's Health, 2019
Purpose In this study, we aimed to determine the role of extracorporeal shockwave therapy (ESWT) in the management of Peyronie's disease (PD). Materials and Methods A total of 325 patients suffering from PD were enrolled in this single-arm clinical study.
M. di Mauro   +18 more
semanticscholar   +1 more source

Laser Therapy for Peyronie’s Disease: A Randomized Control Double-Blind Pilot Study [PDF]

open access: yes, 2019
Introduction: The management of Peyronie’s disease (PD) has remained a therapeutic dilemma for physicians and there is no gold standard treatment. In this paper, we decided to investigate the beneficial effect of the intralesional administration of ...
Allameh, Farzad   +8 more
core  

Home - About - Disclaimer - Privacy