Results 91 to 100 of about 31,589 (307)

Unveiling PFAS hazard in European surface waters using an interpretable machine-learning model

Environment International
Per- and polyfluoroalkyl substances (PFAS), commonly known as “forever chemicals”, are ubiquitous in surface waters and potentially threaten human health and ecosystems.
Li Zhao, Jian Chen, Jiaqi Wen, Yangjie Li, Yingjie Zhang, Qunyue Wu, Gang Yu   +6 more
doaj   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Recycling of paper, cardboard and its PFAS in Norway

Journal of Hazardous Materials Letters
Per- and polyfluoroalkyl substances (PFAS) have been used in paper products since the 1960s. PFAS emissions during the life cycle of these products have been substantial sources of these substances to the environment.
Håkon A. Langberg, Hans Peter H. Arp, Gabriela Castro, Alexandros G. Asimakopoulos, Heidi Knutsen   +4 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

Advanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs, Valon Gllareva, Lukas Moser, Silvia Pravato, Eric Mora Pimentel, Brigitte Leeners, Martin Ehrbar   +6 more
wiley   +1 more source

Challenges and opportunities for porous media research to address PFAS groundwater contamination

InterPore Journal
Per- and polyfluoroalkyl substances (PFAS) have become one of the most important contaminants due to their ubiquitous presence in the environment and potentially profound impacts on human health and the environment even at parts per trillion (ppt ...
Bo Guo, Mark L. Brusseau
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Cord plasma metabolomic signatures of prenatal per- and polyfluoroalkyl substance (PFAS) exposures in the Boston Birth Cohort

Environment International
Background: Prenatal per- and polyfluoroalkyl substance (PFAS) exposures are associated with adverse offspring health outcomes, yet the underlying pathological mechanisms are unclear.
Zeyu Li, Mingyu Zhang, Xiumei Hong, Guoying Wang, Giehae Choi, Kari C. Nadeau, Jessie P. Buckley, Xiaobin Wang   +7 more
doaj   +1 more source

New PFA prototypes

, 2023
We report on the work to develop the Pandora toolkit software containing Particle Flow Algorithms (PFAs) for reconstructing particles for three next-generation detector themes, namely the emerging technology of dual-readout calorimeters, improving hadronic jets for the future linear collider and using new 3D-readout liquid argon detectors in neutrino ...
openaire   +1 more source

Are There Cost Differences in the Argentinean Pension Fund Industry? An Efficiency Frontier Analysis [PDF]

The purpose of this paper is to study the existence of differences in costs between pension fund administrators (PFAs) through the estimation of an econometric cost frontier for Argentina. Like in other eleven Latin American, and some other Central Asian
Ferro, Gustavo, Romero, Carlos A.
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