Results 21 to 30 of about 419,158 (294)

Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer. [PDF]

open access: yes, 2018
The aim of this study was to assess the potential effects of palbociclib in combination with letrozole on QTc. PALOMA-2, a phase 3, randomized, double-blind, placebo-controlled trial, compared palbociclib plus letrozole with placebo plus letrozole in ...
Durairaj, Chandrasekar   +12 more
core   +2 more sources

Combined Central Retinal Artery and Vein Occlusion with Ischemic Optic Neuropathy After COVID-19 Vaccination

open access: yesInternational Medical Case Reports Journal, 2022
Sol Lee,1 Kamalesh K Sankhala,2 Swaraj Bose,3 Ron P Gallemore1 1Department of Clinical Research, Retina Macula Institute, Torrance, CA, USA; 2Cedars-Sinai Medical Center, Beverly Hills, CA, USA; 3NeuroOphthalmology & Orbital Surgery, Cedars-Sinai Medical
Lee S, Sankhala KK, Bose S, Gallemore RP
doaj  

Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their Families. [PDF]

open access: yes, 2018
IntroductionThe impact of crisaborole ointment, a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild to moderate atopic dermatitis (AD), on quality of life (QoL) was assessed in two identically designed phase 3 studies (AD-301 ...
Boguniewicz, Mark   +7 more
core   +2 more sources

GMO regulation in Europe: undue delegation, abdication or design flaw? [PDF]

open access: yes, 2015
On 22 April 2015 the European Commission published a review of the current GMO legislation (the GM Review) and tabled a proposal for its amendment (the GM Proposal).
Paskalev, Vesco
core   +2 more sources

Public awareness of cancer in the Gaza-Strip: A cross-sectional study [PDF]

open access: yes, 2018
Background: Cancer is one of the leading causes of death worldwide. Most deaths from cancer occurs in low- and middle- income countries, which might be explained by the delayed presentation of the cancer patient.
Abu-Nemer, K.   +11 more
core   +1 more source

Promoting recovery through peer provided interventions -Rajah Experience

open access: yesKerala Journal of Psychiatry, 2019
Peer provided interventions are considered to be an additional approach to treatment as usual for mental illness. The word ‘peer’ stands for the goal of persona empowerment, education and recreation.
Kavitha M A, Nechiyilthody Pfizer
doaj   +1 more source

Enzyme replacement therapy with taliglucerase alfa: 36-month safety and efficacy results in adult patients with Gaucher disease previously treated with imiglucerase. [PDF]

open access: yes, 2016
Taliglucerase alfa is the first available plant cell-expressed human recombinant therapeutic protein. It is indicated for treatment of patients with type 1 Gaucher disease (GD) in adult and pediatric patients in several countries.
Amato, Dominick J   +9 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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