Results 111 to 120 of about 19,054 (239)

Single cell RNA sequencing reveals the reshaping effect of perfluorooctanoic acid on the intestinal microenvironment of mice

Ecotoxicology and Environmental Safety
Perfluorooctanoic acid (PFOA), a prevalent perfluorinated compound pollutants, has been implicated in the development of various gastrointestinal disorders.
Ya Gao, Jiayun Guan, Rui Zhou, Zewei Li, Tianyang Chen, Kaican Yang, Rong Huang, Yue Huang, Siting Zheng, Zhenhua Huang, Xiaoxiang Rong   +10 more
doaj   +1 more source

The blockage of the electron transport chains caused by PFOA isomers induced metabolic damage of Arabidopsis leaves

Environmental Chemistry and Ecotoxicology
Different metabolic damage could be caused by PFOA isomers, although the harm mechanism has not been well studied. The effects of PFOA isomers on Arabidopsis metabolism were investigated using metabolomics, proteomics and molecular docking.
Hao Wang, Jianxiong Mei, Zeying He, Bingjie Liu, Jishi Wang, Yue Geng, Yanwei Zhang   +6 more
doaj   +1 more source

Environmental Human Rights in New York’s Constitution [PDF]

, 2017
There is an environmental case to be made in favor of convening a Constitutional Convention. On the 200th anniversary birth of Henry David Thoreau, we can remember his admonition: “Live in each season as it passes; breathe the air, drink the drink, taste
Robinson, Nicholas A.
core   +1 more source

Epidemiological Risk Assessment for PFOA

ISEE Conference Abstracts, 2018
Introduction: Experimental studies of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) exposure in animals have reported developmental effects, liver and kidney toxicity, immun...
openaire   +1 more source

Gene expression patterns associated with PFOA exposure in Czech young men and women

Environment International
Perfluorooctanoic acid (PFOA), a member of per- and polyfluoroalkyl substances (PFASs), has been widely used in manufacturing for decades. Currently, PFOA is strictly regulated, but due to its high stability and persistence, it is detected in both ...
Barbora Rudzanova, Vojtech Thon, Hana Vespalcova, Christopher J. Martyniuk, Pavel Piler, Martin Zvonar, Jana Klanova, Ludek Blaha, Ondrej Adamovsky   +8 more
doaj   +1 more source

Integrated network toxicology and In Vitro/In Vivo experiments reveal molecular mechanisms of perfluorooctanoic acid exposure affecting intracerebral hemorrhage prognosis

Ecotoxicology and Environmental Safety
The incidence of intracerebral hemorrhage (ICH) is rising, and environmental chemical exposure is now recognized as a major factor contributing to poor cerebrovascular outcomes.
Jia-Wei Wu, Bing-Xin Wang, Peng Wang, Xiao-Wei Sha, Cui-Yan Chen, Zeng-Li Miao, Xu-Dong Zhao, Wei Gao   +7 more
doaj   +1 more source

PFOA in People [PDF]

Environmental Science & Technology, 2007
openaire   +2 more sources

Theoretical studies on the pK~a~ values of perfluoroalkyl carboxylic acids: Chain helicity [PDF]

, 2009
Semiempirical, ab initio, and density functional theory (DFT) studies were conducted on a homologous series of straight chain perfluoroalkyl carboxylic acids (PFCAs) ranging in chain length from C~1~ (trifluoroacetic acid; TFA) to C~9~ (perfluorodecanoic
Kaya Forest, Sierra Rayne
core  

Network toxicology of perfluorooctanoic acid-induced hepatointestinal injury and the protective effect of Lycium barbarum polysaccharides against perfluorooctanoic acid in broilers

Poultry Science
Given the extensive organ toxicity of perfluorooctanoic acid (PFOA), this study aimed to elucidate its mechanisms of hepatointestinal toxicity and to evaluate the protective efficacy of Lycium barbarum polysaccharides (LBP). In the initial phase, network
Nana Gao, Fang Huang, Yang Li, Yujia Wu, Heping Bai, Xu Liu, Xiaodan Wang   +6 more
doaj   +1 more source

Therapeutic intervention with anti-TNF alleviates colonic and hepatic toxicity induced by perfluorooctanoic acid (PFOA)Mendeley Data

Ecotoxicology and Environmental Safety
Perfluorooctanoic acid (PFOA) is a prevalent and chemically stable environmental contaminant. Our preliminary data suggest that chronic exposure to PFOA induces colonic damage in mice that resembles inflammatory bowel disease (IBD).
Wei Li, Yongjing Qian, Xiaojing Cai, Yu He, Xiannan Meng, Ling Zhang   +5 more
doaj   +1 more source