Results 111 to 120 of about 29,416 (304)

Multistressor Interaction of Perfluorooctane Sulfonate (PFOS) and Temperature in Two Estuarine Fish Species, Red Drum (Sciaenops ocellatus) and Sheepshead Minnow (Cyprinodon variegatus)

Environmental Toxicology, EarlyView.
ABSTRACT Perfluorooctane sulfonate (PFOS), a perfluoroalkyl substance (PFAS), is characterized by a long, fluorinated carbon chain which makes it ideal for oil‐ and water‐repellent products but detrimental for the environment, where it persists and accumulates in organisms.
Anna L. Thornton, Katy W. Chung, Peter B. Key, Emily C. Pisarski, Philip Tanabe, Marie E. DeLorenzo   +5 more
wiley   +1 more source

Perfluorooctane sulfonate (PFOS) induced bone loss by inhibiting FoxO1-mediated defense against oxidative stress in osteoblast

Ecotoxicology and Environmental Safety
Exposure to perfluorooctane sulfonate (PFOS) has been associated with lower bone density and the occurrence of osteoporosis in human studies, but the effects and mechanisms of PFOS induces bone loss is not well understood.
Liming Xue, Jiale Xu, Ping Xiao, Yiping Jiang, Yuanjie Lin, Chao Feng, Yu’e Jin, Zhijun Zhou, Guoquan Wang, Dasheng Lu   +9 more
doaj   +1 more source

Care Providers of Indigenous Children and Youth in the Child Welfare System: A Scoping Review

Child &Family Social Work, EarlyView.
ABSTRACT Indigenous children continue to be significantly over‐represented in child welfare systems in Canada, the United States, Australia and New Zealand. This scoping review represents a subset of a larger review, the objective of which was to consolidate the extant literature on Indigenous child welfare.
Amanda R. Ervin, Anika J. Dirk, Hannah I. Odekina, Fatemeh Sahlehi Shahrabi, Chloe E. Luck, Mary C. Greenshields, Janice M. Victor   +6 more
wiley   +1 more source

Autophagy-dependent lysosomal calcium overload and the ATP5B-regulated lysosomes-mitochondria calcium transmission induce liver insulin resistance under perfluorooctane sulfonate exposure

Ecotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS), an officially listed persistent organic pollutant, is a widely distributed perfluoroalkyl substance. Epidemiological studies have shown that PFOS is intimately linked to the occurrence of insulin resistance (IR). However,
Jixun Li, Yu Ma, Tianming Qiu, Jianyu Wang, Jingyuan Zhang, Xiance Sun, Liping Jiang, Qiujuan Li, Xiaofeng Yao   +8 more
doaj   +1 more source

Efficient Reductive Defluorination of Branched PFOS by Metal–Porphyrin Complexes

, 2022
Jun Sun, Sreenu Jennepalli, Matthew Lee, Adele M. Jones, Denis M. O’Carroll, Michael Manefield, Mohan Bhadbhade, Björn Åkermark, Biswanath Das, Naresh Kumar   +9 more
openalex   +2 more sources

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Perfluorooctane sulfonate induces ferroptosis-dependent non-alcoholic steatohepatitis via autophagy-MCU-caused mitochondrial calcium overload and MCU-ACSL4 interaction

Ecotoxicology and Environmental Safety
The incidence of nonalcoholic steatohepatitis (NASH) is related with perfluorooctane sulfonate (PFOS), yet the mechanism remains ill-defined. Mounting evidence suggests that ferroptosis plays a crucial role in the initiation of NASH.
Siyu Ren, Jianyu Wang, Zhanchen Dong, Jixun Li, Yu Ma, Ying Yang, Tian Zhou, Tianming Qiu, Liping Jiang, Qiujuan Li, Xiance Sun, Xiaofeng Yao   +11 more
doaj   +1 more source

Biological Markers of PFO-Related Stroke Recurrence

, 2022
Zhuonan Wu, Chuanjing Zhang, Hangyuan Guo, Jufang Chi   +3 more
openalex   +1 more source

Microplastic Impacts on Seafood: A Global Synthesis of Experimental Findings

Fish and Fisheries, EarlyView.
ABSTRACT Plastic pollution is a growing global concern, with plastic and microplastic particles now widespread in aquatic environments. Microplastics are frequently ingested by marine organisms, including commercially important seafood species. Ingestion can lead to a range of biological effects, influenced by the size, type and quantity of plastic, as
Nina Wootton, Patrick Reis‐Santos, Rhiannon A. Van Eck, Isaac Duke, Bronwyn M. Gillanders   +4 more
wiley   +1 more source

Sustainability Assessment of Alternative Methods for Destruction of Per‐ and Polyfluoroalkyl Substances (PFAS) in Water

Remediation Journal, Volume 36, Issue 2, Spring 2026.
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants widely recognized for their resistance to degradation and potential adverse health effects. The treatment of PFAS‐contaminated aqueous media (e.g., drinking water, wastewater, and leachate) has been extensively studied in the published literature; however, the
Mohamed S. Mohamed, Krishna R. Reddy
wiley   +1 more source