Results 81 to 90 of about 1,085 (147)
Human Mutation, Volume 2024, Issue 1, 2024.Glycosylphosphatidylinositols (GPIs) anchor over 150 proteins as GPI‐anchored proteins (GPI‐APs) with crucial roles in diverse biological processes. The highly conserved biosynthesis of GPI‐APs involves precise steps with at least 21 genes, categorized as PIG and PGAP genes.
Seda Susgun +19 more
wiley +1 more source
Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60/S4 cells [PDF]
, 2017 Author Posting. © The Author(s), 2017. This is the author's version of the work. It is posted here by permission of Taylor & Francis for personal use, not for redistribution.
Jauch, Anna +4 more
core +2 more sources
CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders [PDF]
, 2016 Contactin genes CNTN5 and CNTN6 code for neuronal cell adhesion molecules that promote neurite outgrowth in sensory-motor neuronal pathways. Mutations of CNTN5 and CNTN6 have previously been reported in individuals with autism spectrum disorders (ASDs ...
Amsellem, F. +35 more
core +4 more sources
Exploring the role of fibronectin in spondylometaphyseal dysplasia [PDF]
, 2018 La fibronectine (FN), une glycoprotéine largement exprimée, a été associée à de nombreux processus biologiques fondamentaux, mais n’a jamais été impliquée dans des maladies osseuses. L’identification de mutations dans le gène qui code pour cette protéine
Baratang, Nissan Vida
core
Biomarker Discovery with Quantum Neural Networks: A Case-study in CTLA4-Activation Pathways
, 2023 Biomarker discovery is a challenging task due to the massive search space. Quantum computing and quantum Artificial Intelligence (quantum AI) can be used to address the computational problem of biomarker discovery tasks.
Nguyen, Nam
core
Associating expression and genomic data using co-occurrence measures [PDF]
, 2019 Recent technological evolutions have led to an exponential increase in data in all the omics fields. It is expected that integration of these different data sources, will drastically enhance our knowledge of the biological mechanisms behind genomic ...
Larmuseau, Maarten +2 more
core +2 more sources
Biomolecular Events in Cancer Revealed by Attractor Metagenes [PDF]
, 2013 Mining gene expression profiles has proven valuable for identifying signatures serving as surrogates of cancer phenotypes. However, the similarities of such signatures across different cancer types have not been strong enough to conclude that they ...
Anastassiou, Dimitris +2 more
core +3 more sources
, 2022 Molecular subtypes, including the human epidermal growth factor receptor 2-enriched subtype (HER2+), drive patient outcomes in human breast cancer but the biological basis underlying subtype-specific disease is not completely understood (1-4). We mined published microarray data (5, 6) to discover in an unbiased fashion the most distinguishing genetic ...
openaire +1 more source
Abstract PGAP3 is a glycosylphosphatidylinositol (GPI) phospholipase gene localized within chromosome 17q12-21, a region highly linked to asthma. Although much is known about the function of other chromosome 17q12-21 genes expressed at increased levels in bronchial epithelium such as ORMDL3 and GSDMB, little is known about the function ...
Eric Leslie +5 more
openaire +2 more sources
Association between methylation quantitative trait loci and colorectal cancer risk, survival and cancer recurrence [PDF]
Background: Epigenetic changes contribute to colorectal cancer (CRC) pathogenesis. We investigated whether methylation quantitative trait loci (mQTLs) are associated with CRC risk, survival and recurrence.
Din, Farhat V N +10 more
core +1 more source