Results 121 to 130 of about 3,042 (250)

Early tocilizumab and outcomes in acute necrotizing encephalopathy

Developmental Medicine &Child Neurology, EarlyView.
Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han, Prithuja Poudyal, Vanessa Lee, Arushi Gahlot Saini, Shekeeb S Mohammad, Sekhar C Pillai, Gouri Rao Passi, Naveen Sankhyan, Ahmad Rithauddin Mohamed, Lokesh Lingappa, Hiroshi Sakuma, Russell C Dale, Ming Lim, Terrence Thomas, for The International ANE Study Group   +14 more
wiley   +1 more source

A sensitive tool for capturing the development, maintenance, and relapse of internet gaming disorder: Development and validation of the persistent gaming intention scale among Chinese people

Computers in Human Behavior Reports
Background: Internet Gaming Disorder (IGD) is a complex, multifactorial, and dynamic process. Persistent gaming intention plays a key role in the maintenance and relapse of IGD.
Chenguang Zhao, Wenxin Guo, Ziyi Li, Meirewuti Habule, Tiantian Li, Wei Zhang   +5 more
doaj   +1 more source

Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance

The FEBS Journal, EarlyView.
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley   +1 more source

Underdiagnosis of Von Willebrand Disease: The Silent Majority of Women in Brazil

Haemophilia, EarlyView.
Abstract Introduction Von Willebrand disease (VWD) is the most common inherited bleeding disorder. Although autosomal inheritance predicts a similar distribution between sexes, women are more often diagnosed due to hemostatic challenges associated with menstruation and childbirth.
Yara Maria da Silva Pires, Gabriel Iamassaki Staquicini de Paula, Thyago César da Silva Pires   +2 more
wiley   +1 more source

Early On‐Treatment Change in SALT as a Pragmatic Predictor of Ritlecitinib Response in Moderate‐To‐Severe Alopecia Areata: A Real‐World Cohort Study

International Journal of Dermatology, EarlyView.
Ritlecitinib induced rapid clinical improvement in moderate‐to‐severe alopecia areata in real‐world practice. Early change in SALT at Week 12 strongly discriminated Week‐24 responders, supporting a pragmatic treat‐to‐target checkpoint, alongside improvements in clinician‐reported and patient‐reported outcomes and a favorable safety profile.
Giuseppe Gallo, Isotta Giunipero di Corteranzo, Pietro Quaglino, Simone Ribero, Francois Rosset   +4 more
wiley   +1 more source

The study of indirect genetic effects reveals the nature of the home environment – a commentary on Mathias Valstad et al. (2026)

Journal of Child Psychology and Psychiatry, EarlyView.
Valstad et al. (2026) presented important methodological advances in the study of indirect genetic effects in developmental psychology and psychiatry. By combining genetically informative family designs with measured genetic data, they addressed how sibling interaction and genetic nurture may contribute to developmental outcomes such as attention ...
Conor V. Dolan, Alexandra Starr
wiley   +1 more source

Do Genetics Shape Mental Health Trajectories Around Partnership Transitions?

Journal of Marriage and Family, EarlyView.
ABSTRACT Objective This study focuses on the extent to which genetic risk for mental disorders contributes to observed mental health problems before and after partnership transitions. Background Partnership formation and dissolution are linked to short‐term changes in mental health, with outcomes varying by gender, socioeconomic position, and other ...
Philipp Dierker, Maria Gueltzow, Hannu Lahtinen, Mine Kühn, Pekka Martikainen, Mikko Myrskylä   +5 more
wiley   +1 more source

The Development of the European Sleep Questionnaire A New Patient‐Reported Outcome Measure

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep medicine relies on patient‐reported outcome measures (PROMs) to complement clinical interviews and objective sleep tests. Available sleep questionnaires focus on isolated symptoms or single disorders, limiting their ability to capture the complexity of sleep conditions. Also, many PROMs remain poorly validated.
Dirk A. Pevernagie, Marie De Bruecker, Elke Veirman, Geert Crombez, Dimitri M. L. Van Ryckeghem, Katrien Hertegonne, Fré A. Bauters, Inger L. Abma, Erna Sif Arnardottir, Ludger Grote, Jan Hedner, Anna Sigridur. Islind, Kamilla Rún Jóhannsdóttir, Gert Jan Lammers, Walter T. McNicholas, Piet‐Heijn van Mechelen, Kristín Anna Ólafsdóttir, Sebastiaan Overeem, Dieter Riemann, Reijo Sund, An Mariman   +20 more
wiley   +1 more source

PGIS Supported Knowledge Based Participation and Evidences of Empowered Community Members [PDF]

, 2011
In much of Botswana’s rural population, formal business ethic is not common and the business environment contains fragmented and incomplete information. Under such mainly agrarian economies, the villagers do not know where the customers for their produce
Veenendaal, Bert, Mulalu, M.
core  

Cooking Up Cooperation: The Influence of Trust on In‐Group Favoritism

Kyklos, EarlyView.
ABSTRACT Many works highlighted the role of identity in promoting in‐group favoritism, reporting however contrasting empirical results when such behavior entails a personal cost. This paper studies the occurrence of in‐group favoritism within and across communities with heterogeneous generalized trust.
Giovanni Perucca
wiley   +1 more source