Results 21 to 30 of about 3,042 (250)

Expression of Prostacyclin-Synthase in Human Breast Cancer: Negative Prognostic Factor and Protection against Cell Death In Vitro

Mediators of Inflammation, 2015
Endogenously formed prostacyclin (PGI2) and synthetic PGI2 analogues have recently been shown to regulate cell survival in various cell lines. To elucidate the significance of PGI2 in human breast cancer, we performed immunohistochemistry to analyze ...
Thomas Klein, Jens Benders, Friederike Roth, Monika Baudler, Isabel Siegle, Martin Kömhoff   +5 more
doaj   +1 more source

Hypoxia upregulates PGI-synthase and increases PGI2 release in human vascular cells exposed to inflammatory stimuli

Journal of Lipid Research, 2011
Hypoxia affects vascular function and cell metabolism, survival, growth, and motility; these processes are partially regulated by prostanoids. We analyzed the effect of hypoxia and inflammation on key enzymes involved in prostanoid biosynthesis in human ...
Mercedes Camacho, Cristina Rodríguez, Anna Guadall, Sonia Alcolea, Mar Orriols, José-Román Escudero, José Martínez-González, Luis Vila   +7 more
doaj   +1 more source

Human Fallopian Tubes Express Prostacyclin (PGI) Synthase and Cyclooxygenases and Synthesize Abundant PGI [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2002
Animal studies unequivocally support the indispensable role of prostaglandin (PG) and cyclooxygenase (COX) in ovulation and implantation. Available data also suggest that PG and COX may be important in the transport of embryos. The effects of PGE(2) and PGF(2alpha) on the contractility of human tubal muscle have been studied extensively; the expression
Jaou-Chen, Huang, Farinaz, Arbab, Katherine J, Tumbusch, Jennifer S, Goldsby, Nena, Matijevic-Aleksic, Kenneth K, Wu   +5 more
openaire   +2 more sources

Cupin-Type Phosphoglucose Isomerases (Cupin-PGIs) Constitute a Novel Metal-Dependent PGI Family Representing a Convergent Line of PGI Evolution [PDF]

Journal of Bacteriology, 2005
ABSTRACT Cupin-type phosphoglucose isomerases (cPGIs) were identified in some archaeal and bacterial genomes and the respective coding function of cpgi 's from the euryarchaeota Archaeoglobus fulgidus and Methanosarcina mazei , as well as the bacteria
Thomas, Hansen, Bettina, Schlichting, Martina, Felgendreher, Peter, Schönheit   +3 more
openaire   +2 more sources

Can Neogeography and GIS/2 satisfy PGIS? [PDF]

, 2011
The understanding of Participatory Geographical Information Systems (PGIS) is not ascontested as, say, the concepts of participation, or community, or local knowledge.
McCall, M.K.
core   +1 more source

Participatory GIS-Based Approach for the Demarcation of Village Boundaries and Their Utility: A Case Study of the Eastern Boundary of Wilpattu National Park, Sri Lanka

ISPRS International Journal of Geo-Information, 2021
This study examines spatial knowledge of the local community and the participatory resource mapping (PRM) approach to demarcate land boundaries in the eastern boundary of Wilpattu National Park, Sri Lanka. Sri Lanka has four types of major administrative
Chamara J. Hettiarachchi, Prabath Priyankara, Takehiro Morimoto, Yuji Murayama   +3 more
doaj   +1 more source

Does academic performance influence personal growth initiative? An institutional-based study among undergraduate dental students

Journal of Education and Health Promotion, 2018
Introduction: Personal growth initiative (PGI) is an “intentional involvement in changing and developing as a person.” A student who has higher level of PGI is said to show higher academic performance because higher level of PGI might increase the ...
Shiva Kumar Patanapu, Dolar Doshi, Suhas Kulkarni, Padma Reddy, Srilatha Adepu, Srikanth Reddy   +5 more
doaj   +1 more source

Analytical Method Development for 19 Alkyl Halides as Potential Genotoxic Impurities by Analytical Quality by Design

Molecules, 2022
Major issues in the pharmaceutical industry involve efficient risk management and control strategies of potential genotoxic impurities (PGIs). As a result, the development of an appropriate method to control these impurities is required.
Kyoungmin Lee, Wokchul Yoo, Jin Hyun Jeong   +2 more
doaj   +1 more source

Prostacyclin Synthase: Upregulation during Renal Development and in Glomerular Disease as well as Its Constitutive Expression in Cultured Human Mesangial Cells

Mediators of Inflammation, 2015
Prostacyclin (PGI2) plays a critical role in nephrogenesis and renal physiology. However, our understanding of how prostacyclin release in the kidney is regulated remains poorly defined. We studied expression of prostacyclin synthase (PGIS) in developing
Thomas Klein, Günther Klaus, Martin Kömhoff   +2 more
doaj   +1 more source

Seeing landscapes with participatory mapping and PGIS [PDF]

, 2008
Landscapes are place-specific, context specific, though formed by universal processes, dynamic, formed by social forces, contested and negotiated, and perceptually (re-)interpreted.
McCall, M.K.
core   +1 more source