Results 91 to 100 of about 5,679 (109)

Preclinical evaluation of AGT mRNA replacement therapy for primary hyperoxaluria type I disease

Science Advances
Primary hyperoxaluria type 1 (PH1) is a rare inherited liver disorder caused by alanine glyoxylate aminotransferase (AGT) dysfunction, leading to accumulation of glyoxylate which is then converted into oxalate.
Taihua Yang, Jiahao Ge, Lei Huang, Xinye Zhu, Dexin Zhang, Siyuan Tang, Jie Zhao, Yi Hua Ma, Mei Long, Xiaochen Bo, Jie Li, Yiqing Zhang, Q. Yuan, Amar Deep Sharma, Michael Ott, Hongquan Geng, Yicheng Zhao, Liang Zhang, Haifa Shen, Hangwen Li, Dali Li, Ping Wan, Qiang Xia   +22 more
semanticscholar   +1 more source

Recombination between homoeologous chromosomes induced in durum wheat by the Aegilops speltoides Su1-Ph1 suppressor

Theoretical and Applied Genetics, 2019
Hao Li, Le Wang, M. Luo, Fang Nie, Yun Zhou, P. McGuire, A. Distelfeld, Xiongtao Dai, Chunpeng Song, J. Dvorak   +9 more
semanticscholar   +1 more source

The novel function of the Ph1 gene to differentiate homologs from homoeologs evolved in Triticum turgidum ssp. dicoccoides via a dramatic meiosis-specific increase in the expression of the 5B copy of the C-Ph1 gene

Chromosoma, 2019
Kanwardeep S. Rawale, M. A. Khan, K. Gill   +2 more
semanticscholar   +1 more source

Evidence of an Unidentified Extracellular Heat-Stable Factor Produced by Lysobacter enzymogenes (OH11) that Degrade Fusarium graminearum PH1 Hyphae

Current Microbiology, 2017
B. Odhiambo, Gaoge Xu, Guoliang Qian, Fengquan Liu   +3 more
semanticscholar   +1 more source

Homoeologous recombination in the presence of Ph1 gene in wheat

Chromosoma, 2016
D. Koo, Wenxuan Liu, B. Friebe, B. Gill
semanticscholar   +1 more source

Isolation and Genome Sequencing of a Novel Pseudoalteromonas Phage PH1

Current Microbiology, 2016
Zhao-yang Liu, Min Wang, Xue Meng, Yan Li, Duo-bing Wang, Yong Jiang, Hongbing Shao, Yaoyuan Zhang   +7 more
semanticscholar   +1 more source

Safety, efficacy and survival of patients with primary malignant brain tumours (PMBT) in phase I (Ph1) trials: the 12-year Royal Marsden experience

Journal of Neuro-Oncology, 2018
N. Coleman, V. Michalarea, S. Alken, K. Rihawi, R. P. Lopez, N. Tunariu, A. Petruckevitch, L. R. Molife, U. Banerji, J. D. de Bono, L. Welsh, F. Saran, Juanita Lopez   +12 more
semanticscholar   +1 more source

Stones: A novel RNAi therapy for PH1

Nature Reviews Nephrology, 2016
Ellen F. Carney
semanticscholar   +1 more source

The control of recombination in wheat by Ph1 and its use in breeding.

Methods in molecular biology, 2014
G. Moore
semanticscholar   +1 more source

Molecular characterization of Ph1 as a major chromosome pairing locus in polyploid wheat

Nature, 2006
S. Griffiths, R. Sharp, T. Foote, I. Bertin, M. Wanous, S. Reader, I. Colas, G. Moore   +7 more
semanticscholar   +1 more source