Results 151 to 160 of about 15,603 (299)
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Vulnerabilidade do aquífero livre em leques aluviais do sul de Santa Catarina sob arroz irrigado [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em Geografia, Florianópolis, 2015.Predominantemente o cultivo de arroz irrigado no extremo sul do estado de Santa Catarina é ...
Back, Marcos
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
O pH do solo é uma determinação da concentração de íons H+ na solução do solo, que tem influência na disponibilidade de ...
CAMPOS, D. V. B. de +2 more
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Variabilidade espacial de propriedades fisicas do solo em area de mineração [PDF]
Orientador: Celso Luiz PrevedelloDissertação (mestrado) - Universidade Federal do Parana, Setor de Ciencias AgrariasResumo: Objetivando avaliar a magnitude da variação espacial de propriedades físicas do solo em área submetida à exploração mineral do ...
Lange Junior, Francisco Lothar Paulo
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A combined finite element and phase‐field approach predicts the evolution of microstructure during the directional solidification of Ni‐based superalloys. The model reveals how withdrawal rate, temperature gradient, and wall thickness control the dendrite spacing, highlighting the strong effect of surface regions in thin sections where dendrite growth ...
Sean Böhm +3 more
wiley +1 more source
Dinâmica do amônio e do pH na solução de solos com diferentes níveis de salinidade, cultivados com arroz irrigado [PDF]
Rice in Rio Grande do Sul State is grown mostly under flooding, which induces a series of chemical, physical and biological changes in the root environment. These changes, combined with the presence of rice plants, affect the availability of exchangeable
Carmona, Felipe de Campos +2 more
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Evaluating Energy Absorption Performance of Filled Lattice Structures
Maximum stress must be considered to robustly evaluate energy absorber designs. This approach was applied to compare all types of absorbers in a single Ashby diagram and determine the utility of filling lattice voids with a second material. High‐performance fillers can improve the performance of lattices that are limited by buckling or catastrophic ...
Christian Bonney +2 more
wiley +1 more source
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan +5 more
wiley +1 more source
Variáveis de acidez em função da mineralogia do solo
Orientador: Antonio Carlos Vargas MottaCo-orientadores: Vander de Freitas Melo e Valmiqui Costa LimaDissertaçao (mestrado) - Universidade Federal do Paraná, Setor de Ciencias Agrárias, Programa de Pós-Graduaçao em Ciencias do Solo.
Silva, Valentim da, 1977- +1 more
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