Results 151 to 160 of about 127,368 (296)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Slow effects in the pH-step response of silicon nitride ISFET sensors
, 2022 Investigations has been carried out with S3N4-gateinsulator ISFETs to get a more complete database and a deeper understanding of the underlying physical and electrochemical effects.
Woias, P., Fröstl, P., Meixner, L.
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
THE pH VALUE CHANGES IN THE PERIODONTAL POCKETS
, 1996 Many studies have been done of the pH values in periodontal pockets These studies have suggested that the pH value was influenced by the condition of the surrounding tissue.
SOEDA, Wataru +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Robust Sensor for Inline pH Measurements
IEEE Sensors JournalConventionally, a pH sensor having a glass bulb and a liquid-based reference electrode is used for accurate, real-time pH measurement. However, glass bulb-based pH sensors suffer wear and tear in harsh operating conditions and yield erroneous readings in strong alkaline and acidic media.
Nikila Nair +4 more
openaire +2 more sources
pH sensors in the plant apoplast: a sine qua non of phenotypic plasticity. [PDF]
Front Plant Sci, 2023 Vélez-Bermúdez IC, Schmidt W.
europepmc +1 more source
Ocean sensors - for marine environmental monitoring
, 2010 Various sensors and instruments were developed to measure the chemical and physical properties of sea water, but many are expensive and too large to be used on mass deployed vehicles such as the Argo float and submersed gliders.
Gong, Weidong
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Aggregating multiple body sensors for analysis in sports [PDF]
, 2008 Real time monitoring of the wellness of sportspersons, during their sporting activity and training, is important in order to maximise performance during the sporting event itself and during training, as well as being important for the health of the ...
Zhang, Ke +9 more
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