Results 61 to 70 of about 2,339,090 (251)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Repetitive Measurements of Physiological pH by Implantable Optical Sensors in Muscles of adult Danio rerio: Preliminary Results [PDF]

Journal of Stress Physiology & Biochemistry, 2016
Encapsulated optical sensors are promising tool for measurements of physiological parameters inside living organisms. In the present study we tested the possibility to apply encapsulated fluorescent sensors to measure pH in muscles of adult Danio rerio ...
E.V. Borvinskaya, A.N. Gurkov, E.P. Shchapova, B.K. Baduev, I.A. Belousova, I.V. Meglinski, M.A. Timofeyev   +6 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Automation of Water Treatment System with pH Sensors, Conductivity Sensors and Turbidity Sensors Based on Microcontroller

Jurnal Jaringan Telekomunikasi
Water is main need for humans. People living around river use river water as consumsion, but majority of urban rivers are polluted. Polluted river water contains dissolved solids, unsTable water pH content and water turbidity.
Mitsal Iqbal Fadhlurrahman, Farida Arinie Soelistianto, Ahmad Wahyu Purwandi   +2 more
doaj   +1 more source

Piezoresistive Chemical Sensors Based on Functionalized Hydrogels

Chemosensors, 2014
Thin films of analyte-specific hydrogels were combined with microfabricated piezoresistive pressure transducers to obtain chemomechanical sensors that can serve as selective biochemical sensors for a continuous monitoring of metabolites. The gel swelling
Margarita Guenther, Thomas Wallmersperger, Gerald Gerlach   +2 more
doaj   +1 more source

Electronic Sensor for pH Measurements in Nanoliters

Procedia Engineering, 2014
An original design is proposed for the fabrication of an electronic sensor. The device consists on a field effect transistor (FET) combined with an integrated microfluidic channel and is devoted to charges detection in liquids. The technological process has been optimized.
Bouhadda, Ismaïl, de Sagazan, Olivier, Le Bihan, France   +2 more
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Optical fiber pH sensors based on layer-by-layer electrostatic self-assembled Neutral Red

, 2008
The layer-by-layer (LbL) electrostatic self-assembly technique was used for fabricating evanescent wave optical fiber pH sensors based on the colorimetric pH indicator Neutral Red (NR).
Matías, I. R., Goicoechea, J., Arregui, F. J., Zamarreño, C. R.   +3 more
core   +1 more source

Optical sensor for interstitial pH measurements

Journal of Biomedical Optics, 2007
An optical fiber sensor for measuring the pH in interstitial fluid is described. Microdialysis is the approach followed for extracting the sample from the subcutaneous adipose tissue. The interstitial fluid drawn flows through a microfluidic circuit formed by a microdialysis catheter in series with a pH glass capillary. The pH indicator (phenol red) is
Baldini, Francesco, Giannetti, Ambra, Mencaglia, Andrea A.   +2 more
openaire   +3 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source