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Phage diversity, genomics and phylogeny [PDF]
Recent advances in viral metagenomics have enabled the rapid discovery of an unprecedented catalogue of phages in numerous environments, from the human gut to the deep ocean. Although these advances have expanded our understanding of phage genomic diversity, they also revealed that we have only scratched the surface in the discovery of novel viruses ...
Frank Oechslin, Sylvain Moineau
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Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2002
Marine phages are the most abundant biological entities in the oceans. They play important roles in carbon cycling through marine food webs, gene transfer by transduction and conversion of hosts by lysogeny. The handful of marine phage genomes that have been sequenced to date, along with prophages in marine bacterial genomes, and partial sequencing of ...
Anca M. Segall+3 more
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Marine phages are the most abundant biological entities in the oceans. They play important roles in carbon cycling through marine food webs, gene transfer by transduction and conversion of hosts by lysogeny. The handful of marine phage genomes that have been sequenced to date, along with prophages in marine bacterial genomes, and partial sequencing of ...
Anca M. Segall+3 more
openaire +2 more sources
The genomes and comparative genomics of Lactobacillus delbrueckii phages
Archives of Virology, 2011Lactobacillus delbrueckii phages are a great source of genetic diversity. Here, the genome sequences of Lb. delbrueckii phages LL-Ku, c5 and JCL1032 were analyzed in detail, and the genetic diversity of Lb. delbrueckii phages belonging to different taxonomic groups was explored.
Tapani Alatossava+2 more
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Popping the cork: mechanisms of phage genome ejection
Nature Reviews Microbiology, 2013Sixty years after Hershey and Chase showed that nucleic acid is the major component of phage particles that is ejected into cells, we still do not fully understand how the process occurs. Advances in electron microscopy have revealed the structure of the condensed DNA confined in a phage capsid, and the mechanisms and energetics of packaging a phage ...
Ian J Molineux, Debabrata Panja
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The Genome of φAsp2, an Actinoplanes Infecting Phage
Virus Genes, 2004The first genome of a virus infecting a representative of the eubacterial genus Actinoplanes is presented. Phage phiAsp2 has a circularly permutated chromosome that consists of 58,638 bp; its G/C-bias of 70.39% resembles the hosts G + C-content (71-73% within the genus).
Martin Jarling+3 more
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Phage DNA Extraction, Genome Assembly, and Genome Closure
2023Bacteriophages, or more simply phages, are currently experiencing a renaissance in life science research for their roles in natural microbial communities, their potential use as antimicrobials, and biotechnological applications. In the modern era, one of the primary steps in phage characterization is obtaining the sequence of the complete genome; this ...
Justin, Boeckman+3 more
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