Results 351 to 360 of about 420,323 (395)

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source

Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes. [PDF]

PLoS Pathog
Ngotho P, Dantzler Press K, Peedell M, Muasya W, Omondi BR, Otoboh SE, Gomez J, Coronado L, Seydel KB, Kapulu M, Laufer M, Taylor T, Bousema T, Marti M.   +13 more
europepmc   +1 more source

Identification of crucial genes for polycystic ovary syndrome and atherosclerosis through comprehensive bioinformatics analysis and machine learning

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify potential biomarkers in patients with polycystic ovary syndrome (PCOS) and atherosclerosis, and to explore the common pathologic mechanisms between these two diseases in response to the increased risk of cardiovascular diseases in patients with PCOS.
Lirong Wang, Yanli Zhang, Fan Ji, Zhenmin Si, Chengdong Liu, Xiaoke Wu, Chichiu Wang, Hui Chang   +7 more
wiley   +1 more source

A Case of Hemophagocytic Lymphohistiocytosis During Immune Checkpoint Inhibitor Treatment for Metastatic Renal Cell Carcinoma, Complicated by Pancytopenia Attributed to Cytomegalovirus Infection

IJU Case Reports, EarlyView.
ABSTRACT Introduction Hemophagocytic lymphohistiocytosis (HLH) is characterized by macrophage and cytotoxic lymphocyte hyperactivation, fever, pancytopenia, liver dysfunction, and abnormal coagulation. However, no specific treatments have been established for HLH caused by immune checkpoint inhibitors.
Tomoko Honda, Hirohito Naito, Yu Osaki, Yoichiro Tohi, Yuki Matsuoka, Takuma Kato, Homare Okazoe, Rikiya Taoka, Nobufumi Ueda, Mikio Sugimoto   +9 more
wiley   +1 more source

Therapeutic mitochondria treatment amplifies macrophage-mediated phagocytosis and recycling exocytosis. [PDF]

J Cereb Blood Flow Metab
Tanaka M, Ishikane S, Back DB, Licastro E, Zhang F, Park JH, Esposito E, Pignataro G, Nakano T, Nakamura Y, Hayakawa K.   +10 more
europepmc   +1 more source

A small molecule esculetin accelerates postprandial lipid clearance involving activation of C/EBPβ and CD36-mediated phagocytosis by adipose tissue macrophages. [PDF]

Theranostics
Wang G, Li Z, Ni W, Ye H, Liu Y, Chen L, Wang L, Liu C, Chen J, Wang X, Ding X, Zhao L, Ge X, Wang Y, Ye Y, Kiwa T, Zang L, Wang J, Dai C, Liu B.   +19 more
europepmc   +1 more source

rFIP-nha activates macrophages towards a pro-inflammatory phenotype via AIM2 inflammasome modulation. [PDF]

Front Cell Dev Biol
Liu Y, Li Z, Wichers H, Bastiaan-Net S, Hoppenbrouwers T.   +4 more
europepmc   +1 more source

Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities. [PDF]

Signal Transduct Target Ther
Reschke R, Enk AH, Hassel JC.
europepmc   +1 more source

Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy. [PDF]

Front Immunol
Krishnamoorthy M, Seelige R, Brown CR, Chau N, Nielsen Viller N, Johnson LDS, Linderoth E, Wang JCY, Dillon CP, Abayasiriwardana K, Lees C, Wong M, Kaneda MM, Uger RA, Lin GHY.   +14 more
europepmc   +1 more source

The dual role of microglia in Alzheimer's disease: from immune regulation to pathological progression. [PDF]

Front Aging Neurosci
He C, Chen B, Yang H, Zhou X.
europepmc   +1 more source