Results 131 to 140 of about 87,347 (268)
An improved Scale-Invariant Feature Transform-based method for detecting tumor tissue motion induced by respiration. [PDF]
Pan Q +5 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A phantom decoy shifts wild forager decisions in a natural environment. [PDF]
Jarvis GR +5 more
europepmc +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Quality control of opportunistic multi-energy CT bone mineral density quantification. [PDF]
Thompson EA +5 more
europepmc +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
W R, HENDERSON, G E, SMYTH
openaire +2 more sources
Effect of Phantom Containing Implants Angulation on the Amount of Metal Artifacts Around the Implants in CBCT Images. [PDF]
Valizadeh S +5 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Impact on PET spatial resolution through positron range confinement in a high magnetic field across tissue-equivalent materials. [PDF]
Lopez-Berenguer F +5 more
europepmc +1 more source

